2-Hydroxy-5,7-dimethylquinoline-3-carboxylic acid CAS 436087-35-3
| CAS No. | 436087-35-3 |
| Molecular Formula | C12H11NO3 |
| Molecular Weight | 217.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Hydroxy-5,7-dimethylquinoline-3-carboxylic acid (CAS 436087-35-3) is a high-purity analytical reference standard with the molecular formula C12H11NO3 and a molecular weight of 217.22 g/mol.
The molecular framework of 2-Hydroxy-5,7-dimethylquinoline-3-carboxylic acid (C12H11NO3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H11NO3 |
| Molecular Weight | 217.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
Related Hydroxy Standards
- Methyl 3-hydroxy-2-methylquinoline-4-carboxylate (CAS 104179-54-6)
- 2-Hydroxy-1-(2-methoxyquinolin-3-yl)ethan-1-one (CAS 1125845-79-5)
- Methyl 4-hydroxy-2-methylquinoline-7-carboxylate (CAS 1150618-19-1)
- Methyl 1-hydroxy-3-methylisoquinoline-7-carboxylate (CAS 1264209-77-9)
- 3-Hydroxy-3-(quinolin-6-yl)propanoic acid (CAS 1343016-11-4)
- Methyl 3-hydroxy-4-(1H-pyrrol-1-yl)benzoate (CAS 1346498-99-4)
- Methyl 2-hydroxy-2-(quinolin-3-yl)acetate (CAS 1479466-07-3)
- 2-Hydroxy-3-(quinolin-4-yl)propanoic acid (CAS 1492805-64-7)
Recommended Standards
- 2-Hydroxy-3-(quinolin-2-yl)propanoic acid (CAS 458561-90-5)
- 2-Hydroxy-5,8-dimethylquinoline-3-carboxylic acid (CAS 436087-34-2)
- 2-Ethyl-3-hydroxyquinoline-4-carboxylic acid (CAS 811432-22-1)
- 2-Hydroxy-6,8-dimethylquinoline-3-carboxylic acid (CAS 436087-33-1)
- 6-Methyl-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carbonitrile (CAS 1279204-24-8)
- (3-(Pyridin-2-yl)-1H-pyrazol-5-yl)methanol (CAS 828911-09-7)
- N-(6-(Pyrrolidin-1-yl)pyrimidin-4-yl)benzofuran-2-carboxamide (CAS 1396812-08-0)
- 5-Iodo-2-((5-(trifluoromethyl)pyridin-2-yl)oxy)benzonitrile (CAS 1369255-12-8)
- Pyrazoloquinolone Impurity 7 (CAS CATO-C4X-23897)
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- 6-Fluoro-5-methyl-1H-indole (CAS 162100-95-0)
- 2-[(Methylsulfonyl)methylene]-1,3-thiazolidin-4-one (CAS 24146-38-1)
- 1,4-Diamino-7-chloro-2-(4-fluorophenoxy)anthracene-9,10-dione (CAS 88605-31-6)
- 59880-97-6 Chemotactic peptide F-Met-Leu-Phe L-Phenylalanine, N-(N-(N-formyl-L-methionyl)-L-leucyl)- N-Formyl-L-methionyl-L-leucyl-L-phenylalanine N-Formyl-Met-Leu-Phe N-Formylmethionine leucyl-phenylalanine fMLF fMLP (misnomer but widely used) (CAS 59880-97-6)
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