1-(4-Fluorobenzoyl)piperidine-3-carboxylic acid CAS 436093-16-2
| CAS No. | 436093-16-2 |
| Molecular Formula | C13H14FNO3 |
| Molecular Weight | 251.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 251.25 g/mol gives 1-(4-Fluorobenzoyl)piperidine-3-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(4-Fluorobenzoyl)piperidine-3-carboxylic acid (CAS 436093-16-2), molecular formula C13H14FNO3 and molecular weight 251.25 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(4-Fluorobenzoyl)piperidine-3-carboxylic acid (C13H14FNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H14FNO3 |
| Molecular Weight | 251.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluorobenzoyl Standards
- 1-(4-Fluorobenzoyl)piperidine-4-carboxylic acid (CAS 139679-45-1)
- 1-(2-Fluorobenzoyl)piperidine-4-carboxylic acid (CAS 445226-98-2)
- 1-(3-Fluorobenzoyl)piperidine-4-carboxylic acid (CAS 436093-13-9)
- 1-(4-Fluorobenzoyl)piperidine-2-carboxylic acid (CAS 351902-40-4)
- 3-(4-Fluorobenzoyl)quinoline (CAS 1183511-02-5)
- 4-(4-Fluorobenzoyl)isoquinoline (CAS 1187168-98-4)
- 4-(4-Fluorobenzoyl)quinoline (CAS 169957-25-9)
- 4-(3-Fluorobenzoyl)quinoline (CAS 1706436-13-6)
Recommended Standards
- 1-[2-(4-fluorophenyl)ethyl]-5-oxopyrrolidine-3-carboxylic acid (CAS 842971-84-0)
- 2-(4-Fluorophenyl)-2-(4-oxopiperidin-1-yl)aceticacid (CAS 886363-63-9)
- 1-(3-Fluorobenzamido)cyclopentane-1-carboxylic acid (CAS 912771-14-3)
- 3,3-Bis(1-Methylethyl)-1-(2,2,2-Trifluoroethyl)-2,4-Azetidinedione (CAS 56519-50-7)
- 4-((Isopropylamino)methyl)benzoic acid (CAS 96084-40-1)
- 5-Bromo-1,3-dimethyl-1H-indole-7-carbonitrile (CAS 1221448-62-9)
- tert-Butyl 2-(aminooxy)acetate (CAS 56834-02-7)
- 4-((2-Chloro-6-fluorobenzylidene)amino)-3-(m-tolyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 478255-65-1)
- 2-(Pyrrolidin-3-yl)propan-2-ol hydrochloride (CAS 1357923-37-5)
- 2-(4-(Methoxymethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 675605-92-2)
- 448939-97-7 2-Chloro-N-[5-methyl-4-(4-methylphenyl)-1,3-thiazol-2-yl]acetamide MFCD02358966 (CAS 448939-97-7)
- Methyl 2-Oxovalerate (CAS 6376-59-6)
- 2-Chloro-2-Fluoro-1-(4-Methoxy-3-Methylphenyl)Ethanone (CAS 58750-70-2)
- Semaglutide impurity 195 (CAS CATO-C4X-2226195)
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