6-Hydroxy-2-oxo-1,2-dihydroquinoline-4-carboxylic acid CAS 4363-99-9
| CAS No. | 4363-99-9 |
| Molecular Formula | C9H9N3O2S2 |
| Molecular Weight | 255.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Hydroxy-2-oxo-1,2-dihydroquinoline-4-carboxylic acid (CAS 4363-99-9), molecular formula C9H9N3O2S2 and molecular weight 255.32 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Hydroxy-2-oxo-1,2-dihydroquinoline-4-carboxylic acid (C9H9N3O2S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-Hydroxy-2-oxo-1,2-dihydroquinoline-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H9N3O2S2 |
| Molecular Weight | 255.32 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
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Recommended Standards
- 5-((Phenylsulfonyl)methyl)-1,3,4-thiadiazol-2-amine (CAS 88743-06-0)
- BMS-345541 (CAS 445430-58-0)
- 5-((4-Aminophenyl)sulfonyl)thiazol-2-amine (CAS 473-30-3)
- Ethyl 7-(methylthio)thiazolo[5,4-d]pyrimidine-2-carboxylate (CAS 866410-58-4)
- (R)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-(3,5-bis(trifluoromethyl)benzyl)propanoic acid (CAS 1260587-04-9)
- 1-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]-5-methyl-1H-pyrazol-3-amine (CAS 2097935-96-9)
- 1-(1-Ethyl-1h-1,2,4-triazol-5-yl)propan-2-one (CAS 1480773-03-2)
- NefopaM N-Oxide DiHCl (CAS CATO-C4X-283719)
- 7690AH 915706-90-0 C29H22NO4Pol Sieber amide resin (CAS 915706-90-0)
- Methyl 2-(4-(aminomethyl)phenyl)-2,2-difluoroacetate (CAS 2120774-76-5)
- 2-Chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-(furan-2-ylmethyl)acetamide (CAS 850764-24-8)
- 4-(3-Chlorophenyl)-1-(3-nitrophenyl)-1H-pyrazol-5-amine (CAS 324008-93-7)
- Brivaracetam Impurity 193 (CAS CATO-C4X-2007193)
- Semaglutide Impurity 149 (CAS CATO-C4X-2226149)
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