Lansoprazole Impurity 49 HCl CAS 4370-22-3
| CAS No. | 4370-22-3 |
| Molecular Formula | C7H8ClN |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Lansoprazole Impurity 49 HCl (CAS 4370-22-3), a pharmacopoeial impurity reference standard (molecular formula C7H8ClNHCl, MW 178.06 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrile group, chlorine substitution, Lansoprazole Impurity 49 HCl is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 178.06 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H8ClN HCl |
| Molecular Weight | 178.06 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Lansoprazole Standards
- Lansoprazole EP Impurity D (CAS 102976-62-5)
- Lansoprazole Impurity 37 (CAS 103312-62-5)
- Lansoprazole EP Impurity C/USP Impurity B (CAS 103577-40-8)
- Lansoprazole (CAS 103577-45-3)
- Lansoprazole Impurity 45 (CAS 103577-61-3)
- Lansoprazole Impurity 51 (CAS 103577-66-8)
- Lansoprazole Impurity 18 (CAS 1083100-26-8)
- Lansoprazole Impurity 10 (CAS 1083100-27-9)
Recommended Standards
- Dabigatran Impurity 120 (CAS CATO-C4X-1089120)
- Sugammadex Impurity Org48302 (CAS 2376607-98-4)
- Ticagrelor Impurity N2 (CAS 1863036-49-0)
- Ethyl 4-(Methylamino)-3-nitrobenzoate (CAS 71254-71-2)
- 1-Methoxy-4-(1-methylcyclopropyl)benzene (CAS 63340-01-2)
- Methyl 2-(6-ethyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)-2-oxoacetate (CAS 2055840-31-6)
- 2-Fluoro-N,N-dimethyl-3-nitroaniline (CAS 1369899-53-5)
- tert-Butyl 3,4,9,9a-tetrahydropyrazino[2,1-c][1,4]oxazine-8(1H)-carboxylate (CAS 1810070-10-0)
- 4-Bromo-1-isobutyl-1H-pyrazole-3-carboxylic acid (CAS 1006493-78-2)
- Semaglutide Impurity 146 (CAS 2645421-68-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com