5-(2-(Methylthio)ethyl)-3-phenyl-2-thioxoimidazolidin-4-one CAS 4370-90-5
| CAS No. | 4370-90-5 |
| Molecular Formula | C12H14N2OS2 |
| Molecular Weight | 266.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
5-(2-(Methylthio)ethyl)-3-phenyl-2-thioxoimidazolidin-4-one (CAS 4370-90-5), molecular formula C12H14N2OS2 and molecular weight 266.38 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-(2-(Methylthio)ethyl)-3-phenyl-2-thioxoimidazolidin-4-one (C12H14N2OS2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H14N2OS2 |
| Molecular Weight | 266.38 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Methylthio Standards
- (S)-5-(2-(Methylthio)ethyl)-3-phenyl-2-thioxoimidazolidin-4-one (CAS 29583-09-3)
- 2-(Methylthio)-1,5-diphenyl-1H-imidazole (CAS 136802-80-7)
- 2-(Methylthio)-4,5-diphenyl-1H-imidazole (CAS 3653-22-3)
- 3-(Methylthio)-1,5-diphenyl-1H-pyrazole (CAS 80967-26-6)
- 5-(Methylthio)-1,3-diphenyl-1H-pyrazole (CAS 66040-87-7)
- Ethyl 5-(2-(methylthio)phenyl)-5-oxopentanoate (CAS 951888-98-5)
- Ethyl 5-(4-(methylthio)phenyl)-5-oxopentanoate (CAS 854859-01-1)
- 9-(Methylthio)-5,6-dihydrothieno[3,4-h]quinazoline-2(1H)-thione (CAS 913688-38-7)
Recommended Standards
- 4-tert-Butyl-4-ethylbenzophenone (CAS 952024-41-8)
- 5-(morpholine-4-sulfonyl)pyridine-2-thiol (CAS 852706-13-9)
- 4-tert-Butyl-3,5-dimethylbenzophenone (CAS 55709-39-2)
- 6-(Allyloxy)-4,4,5,8-tetramethylchroman-2-one (CAS 219938-60-0)
- 3-Hydroxy-5-methoxybenzonitrile (CAS 124993-53-9)
- (2,2,3,3-Tetrafluoropropoxy)pentafluorobenzene (CAS 89847-87-0)
- 7-Bromo-2-(3-chlorophenyl)-[1,2,4]triazolo[1,5-a]pyridine (CAS 1893727-19-9)
- Trimethylsilylcyclopentadiene (mixture of isomers) (CAS 25134-15-0)
- 1,4-Dibromobenzene (CAS 106-37-6)
- N-Acetylaminoglutethimide (CAS 38473-28-8)
- n-(2-Ethoxyphenyl)-3,4-dihydro-2h-pyrrol-5-amine (CAS 745028-10-8)
- 2-Amino-4-(pyridin-4-yl)butanamide (CAS 1466214-67-4)
- 1-(4-Nitrophenyl)-3-phenylprop-2-yn-1-one (CAS 3672-66-0)
- Peptide Impurity 12 (CAS CATO-CPTD788812)
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