2-Amino-1-(3-bromo-4-methoxyphenyl)propan-1-one CAS 4374-21-4
| CAS No. | 4374-21-4 |
| Molecular Formula | C10H12BrNO2 |
| Molecular Weight | 258.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-Amino-1-(3-bromo-4-methoxyphenyl)propan-1-one (CAS 4374-21-4) is a high-purity analytical reference standard with the molecular formula C10H12BrNO2 and a molecular weight of 258.11 g/mol.
The molecular framework of 2-Amino-1-(3-bromo-4-methoxyphenyl)propan-1-one (C10H12BrNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H12BrNO2 |
| Molecular Weight | 258.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Amino Standards
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Recommended Standards
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- 2-Amino-4-(4-bromophenyl)butanoic acid (CAS 225233-77-2)
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- 4-(4-Isopropoxyphenyl)cyclohexanone (CAS 365553-47-5)
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- LY 266097 Hydrochloride (CAS 172895-39-5)
- 2-Methoxy-5-methylnicotinaldehyde (CAS 1203499-47-1)
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- 2,6-Dibromoindosalicylic Acid Disodium Salt (CAS 112147-27-0)
- Methyl sorbate (CAS 689-89-4)
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