2,2-Dimethyl-4-phenylbutanoic acid CAS 4374-44-1

Purity 97%+In StockPharmaceutical Standards
CAS No.4374-44-1
Molecular FormulaC12H16O2
Molecular Weight192.25 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,2-Dimethyl-4-phenylbutanoic acid CAS 4374-44-1 chemical structure

Description

The molecular framework of 2,2-Dimethyl-4-phenylbutanoic acid (C12H16O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

2,2-Dimethyl-4-phenylbutanoic acid (CAS 4374-44-1), molecular formula C12H16O2 and molecular weight 192.25 g/mol, is a CATO reference standard with documented purity and traceability.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H16O2
Molecular Weight192.25 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at 2-8°C
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1958

Related Dimethyl Standards

Recommended Standards

Why CATO?