Phthalic Acid, Mono-2-Ethylhexyl Ester CAS 4376-20-9
| CAS No. | 4376-20-9 |
| Molecular Formula | C16H22O4 |
| Molecular Weight | 278.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Phthalic Acid, Mono-2-Ethylhexyl Ester (CAS 4376-20-9), molecular formula C16H22O4 and molecular weight 278.34 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Phthalic Acid, Mono-2-Ethylhexyl Ester (C16H22O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), Phthalic Acid, Mono-2-Ethylhexyl Ester meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H22O4 |
| Molecular Weight | 278.34 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Phthalic Standards
- Phthalic Acid, Bis-Butyl Ester (CAS 84-74-2)
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Recommended Standards
- Mono(2-ethylhexyl) Terephthalate (CAS 155603-50-2)
- Monooctyl Phthalate (CAS 5393-19-1)
- Diisobutyl terephthalate (CAS 18699-48-4)
- tert-butyl 2-(4-aminophenyl)morpholine-4-carboxylate (CAS 1002726-96-6)
- 1-(tert-Butyl) 2-methyl (2S)-5-methoxypyrrolidine-1,2-dicarboxylate (CAS 195964-54-6)
- 2-(1H-Benzo[d]imidazol-5-yl)propanenitrile (CAS 20129-35-5)
- 2-[4-(trifluoromethyl)phenyl]acetamide (CAS 41360-55-8)
- (R)-2-amino-N,N-dimethyl-3-phenylpropanamide hydrochloride (CAS 186432-24-6)
- (11β,13α)-17-(Acetyloxy)-11-[4-(dimethylamino)phenyl]-19-norpregna-4,9-diene-3,20-dione (CAS 96285-40-4)
- (S)-(2-Nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-7-yl)methanol (CAS 1541204-54-9)
- 1-(2-Fluoroethyl)-1H-imidazole-5-carboxylic acid (CAS 1781658-25-0)
- 7-Bromo-4-(2-(cyclohex-1-en-1-yl)ethyl)-4,5-dihydrobenzo[f][1,4]oxazepin-3(2H)-one (CAS 1326898-15-0)
- 4-{2-[(2-Methoxybenzyl)oxy]ethyl}piperidinehydrochloride (CAS 1219949-09-3)
- DAPK Substrate Peptide (CAS 386769-53-5)
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