2-Ethyl-6-fluoro-1H-indole CAS 437717-47-0
| CAS No. | 437717-47-0 |
| Molecular Formula | C10H10FN |
| Molecular Weight | 163.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-Ethyl-6-fluoro-1H-indole (CAS 437717-47-0), molecular formula C10H10FN and molecular weight 163.19 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Ethyl-6-fluoro-1H-indole (C10H10FN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures 2-Ethyl-6-fluoro-1H-indole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H10FN |
| Molecular Weight | 163.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- 2-(4-Fluoro-3,5-dimethylphenyl)acetonitrile (CAS 1000513-61-0)
- 4-Fluoro-5,7-dimethyl-1H-indole (CAS 1190320-77-4)
- 3-Ethyl-7-fluoro-1h-indole (CAS 1360902-63-1)
- 3-Ethyl-6-fluoro-1h-indole (CAS 1360940-05-1)
- 3-Ethyl-5-fluoro-1h-indole (CAS 1360962-77-1)
- 3-Ethyl-4-fluoro-1H-indole (CAS 1360962-90-8)
- 2-Fluoro-4-isopropylbenzonitrile (CAS 1369834-93-4)
- 6-Ethyl-5-fluoro-1H-indole (CAS 1510828-27-9)
Recommended Standards
- 2-(4-Fluorophenyl)-2-methylpropanenitrile (CAS 93748-09-5)
- 2-fluoro-3-morpholino-propan-1-ol (CAS 2304782-14-5)
- 2-(3-Fluorophenyl)-2-methylpropanenitrile (CAS 93748-10-8)
- 3-Fluoro-4,4-dimethoxypiperidine (CAS 355006-64-3)
- 2-Iodo-1,3,4-trimethylbenzene (CAS 41381-32-2)
- 5-(3-Methylphenyl)thiophene-2-carbaldehyde (CAS 38401-69-3)
- Methylcis-3-hydroxy-3-phenyl-cyclobutanecarboxylate (CAS 69584-45-8)
- N-(2-Aminoethyl)-2-[1-[Difluoro[(Trifluorovinyl)Oxy]Methyl]-1,2,2,2-Tetrafluoroethoxy]-1,1,2,2-Tetrafluoroethanesulphonamide (CAS 64346-90-3)
- 2-Amino-5-(aminomethyl)-3-(difluoromethyl)isonicotinic acid (CAS 1803686-14-7)
- Tert-butyl (s)-(1-(4-bromobenzyl)pyrrolidin-3-yl)carbamate (CAS 1286208-27-2)
- 5,5-Dimethylfuran-2,4(3H,5H)-dione (CAS 50630-62-1)
- 1185148-20-2 2-Bromo-3-methylthiophene-d3 (CAS 1185148-20-2)
- Dapagliflozin Impurity 155 (CAS CATO-C4X-1138155)
- Endo-Ala35-Tirzepatide (CAS CATO-CPTD788687)
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