3-Chloro-5-fluoro-4-(hydroxymethyl)phenol CAS 438050-33-0
| CAS No. | 438050-33-0 |
| Molecular Formula | C7H6ClFO2 |
| Molecular Weight | 176.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 3-Chloro-5-fluoro-4-(hydroxymethyl)phenol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
3-Chloro-5-fluoro-4-(hydroxymethyl)phenol (CAS 438050-33-0), molecular formula C7H6ClFO2 and molecular weight 176.57 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 3-Chloro-5-fluoro-4-(hydroxymethyl)phenol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 176.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H6ClFO2 |
| Molecular Weight | 176.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 3-Chloro-5-fluoro-4-methoxyphenol (CAS 1017777-55-7)
- 2-Chloro-6-fluoro-3-methoxyphenol (CAS 1017777-60-4)
- 6-Chloro-2-fluoro-3-methoxyphenol (CAS 1017777-74-0)
- 5-Chloro-2-fluoro-4-methoxyphenol (CAS 1394953-79-7)
- 3-Chloro-2-fluoro-4-methoxyphenol (CAS 1781486-60-9)
- 3-Chloro-6-fluoro-2-methoxyphenol (CAS 1781486-66-5)
- 3-Chloro-4-fluoro-2-methoxyphenol (CAS 1783512-32-2)
- 4-Chloro-3-fluoro-2-methoxyphenol (CAS 1783512-40-2)
Recommended Standards
- (1S)-2,2-difluorocyclopropanesulfonyl chloride (CAS 2740630-26-4)
- 4-Chloro-2-fluoro-3-methoxyphenol (CAS 1993479-29-0)
- 2,2-difluorocyclopropanesulfonyl chloride (CAS 1935280-15-1)
- Ammoxetine Impurity 11 (CAS CATO-C4X-335711)
- 4-Chloro-6-ethyl-5-iodothieno[2,3-d]pyrimidine (CAS 1799610-93-7)
- 3-(Difluoromethoxy)-4-fluoro-5-methylbenzaldehyde (CAS 2090318-51-5)
- 3,3,12,12-Tetramethyl-1,5,10,14-tetraoxadispiro[5.2.5.2]hexadecane (CAS 29280-23-7)
- N-(4-fluorobenzyl)cyclopropanamine (CAS 625437-46-9)
- 2,5-Dichloro-3-(difluoromethoxy)benzenesulfonyl chloride (CAS 1803787-58-7)
- Ethyl 5-benzyl-5,6,7,8-tetrahydro-4H-pyrazolo[1,5-a][1,4]diazepine-7-carboxylate (CAS 2139305-92-1)
- (5S)-5-[3-(1,1,2,2,3,3,3-heptadeuteriopropoxy)-4-methoxyphenyl]-5-methyl-1,3-oxazolidin-2-one (CAS 1795786-04-7)
- 8-Methyl-2,3,4,5-tetrahydropyrido[3,2-f][1,4]oxazepine dihydrochloride (CAS 956431-48-4)
- 4-Allyl-1,2,5-trimethylpiperidin-4-ol (CAS 117273-47-9)
- Tirzepatide Impurity 12 (CAS CATO-C4X-324012)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com