4-Pivalamidobenzenesulfonyl chloride CAS 438191-85-6
| CAS No. | 438191-85-6 |
| Molecular Formula | C11H14ClNO3S |
| Molecular Weight | 275.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Pivalamidobenzenesulfonyl chloride (CAS 438191-85-6), molecular formula C11H14ClNO3S and molecular weight 275.75 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Pivalamidobenzenesulfonyl chloride (C11H14ClNO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Pivalamidobenzenesulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H14ClNO3S |
| Molecular Weight | 275.75 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Recommended Standards
- 4-Chloro-6-methoxy-2-(thiophen-2-yl)quinoline (CAS 954225-75-3)
- 5-((2-Chloro-6-fluorobenzyl)thio)-1,3,4-thiadiazol-2-amine (CAS 660821-10-3)
- 4-[(3-Methylbutanoyl)amino]benzenesulfonyl chloride (CAS 500730-49-4)
- 6-(Benzyloxy)-2-chlorobenzo[d]thiazole (CAS 960535-42-6)
- Ethyl 4-formylbicyclo[2.2.2]octane-1-carboxylate (CAS 959958-67-9)
- 6-Chloroimidazo[1,2-a]pyridine-5-carbonitrile (CAS 1414864-00-8)
- KU-60019 (CAS 925701-46-8)
- Methyl 6-fluoro-2-methoxy-3-methylbenzoate (CAS 2113509-16-1)
- Ethyl 6-bromopyrazolo[1,5-a]pyrimidine-2-carboxylate (CAS 1005209-42-6)
- (R)-(6-Bromo-1,2,3,4-tetrahydronaphthalen-1-yl)methanamine (CAS 1851373-59-5)
- 1-Chloro-2-(2-chloroethyl)-3-fluorobenzene (CAS 958027-86-6)
- Ibuprofen Impurity 64 (CAS CATO-C4X-108264)
- 2-Methyl-6-(2-phenylethenyl)pyridine (CAS 6266-99-5)
- Neuropeptide SF (human) (CAS 192387-39-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com