2-Amino-4-(4-ethylphenyl)-5-methylthiophene-3-carboxamide CAS 438197-57-0
| CAS No. | 438197-57-0 |
| Molecular Formula | C14H16N2OS |
| Molecular Weight | 260.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Amino-4-(4-ethylphenyl)-5-methylthiophene-3-carboxamide (C14H16N2OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
2-Amino-4-(4-ethylphenyl)-5-methylthiophene-3-carboxamide (CAS 438197-57-0) is a high-purity analytical reference standard with the molecular formula C14H16N2OS and a molecular weight of 260.35 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H16N2OS |
| Molecular Weight | 260.35 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Amino Standards
- (2S)-2-amino-3-phenyl-N-(thiophen-2-ylmethyl)propanamide (CAS 762215-56-5)
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Recommended Standards
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- 2-(Butylthio)-6-phenylpyrimidin-4(1H)-one (CAS 62459-14-7)
- 2-Fluoren-9-ylidenemethylthiophene (CAS 843638-98-2)
- Tris(norbornadiene)(acetylacetonato)iridium(III) (CAS 41612-46-8)
- 2,4-Difluorobenzene-1,3-Dicarbonitrile (CAS 73688-94-5)
- (S)-1-(5-Bromothiophen-2-yl)ethan-1-amine hydrochloride (CAS 1807933-94-3)
- 4-(4-Ethoxyphenyl)-4-oxo-2-(pyrrolidin-1-yl)butanoic acid (CAS 301193-75-9)
- 2-[(pyridin-2-yl)formamido]acetic acid (CAS 5616-29-5)
- Benzenamine, 2-(dimethylphosphinyl)-6-fluoro-4-[(4-methoxyphenyl)methoxy]- (CAS 2886000-51-5)
- Linagliptin Impurity 15 (CAS 1791405-13-4)
- Lornoxicam Impurity 11 (CAS CATO-C4X-201611)
- 6-Chloroquinolin-5-ol (CAS 1236162-17-6)
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