2-[3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethyl-4(3H)-quinazolinone CAS 438450-43-2
| CAS No. | 438450-43-2 |
| Molecular Formula | C18H12BrCl2N5O |
| Molecular Weight | 465.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 465.13 g/mol gives 2-[3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethyl-4(3H)-quinazolinone distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-[3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethyl-4(3H)-quinazolinone (CAS 438450-43-2) is a high-purity analytical reference standard with the molecular formula C18H12BrCl2N5O and a molecular weight of 465.13 g/mol.
Structurally, 2-[3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethyl-4(3H)-quinazolinone (C18H12BrCl2N5O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 465.13 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-[3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethyl-4(3H)-quinazolinone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H12BrCl2N5O |
| Molecular Weight | 465.13 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 5 |
Related Bromo Standards
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- Bromo-PEG5-phosphonic acid diethyl ester (CAS 1446282-41-2)
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Recommended Standards
- (2S,4S)-1-(tert-Butoxycarbonyl)-4-(2,4-dibromophenoxy)-2-pyrrolidinecarboxylic acid (CAS 1354487-38-9)
- Sisapronil (CAS 856225-89-3)
- Fluazinam (CAS 79622-59-6)
- (5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-4-hydroxy-4,5-dihydrofuran-2-yl)methyl tetrahydrogen triphosphate (CAS 2514801-98-8)
- 1795031-39-8 Chloranolol-d9 (CAS 1795031-39-8)
- Methyl(methylimino)(4-nitrophenyl)-lambda6-sulfanone (CAS 67087-48-3)
- 2,6-Bis[(4S)-4,5-dihydro-4-(1-methylethyl)-2-oxazolyl]-4-pyridinamine (CAS 860151-85-5)
- N,N-Dimethylformamide-d1 (CAS 2914-27-4)
- N,N-Dimethyl-2-[(pyridin-2-ylmethyl)amino]-ethanesulfonamide dihydrochloride (CAS 1257848-95-5)
- 6-Bromo-4-chloro-2-(4-methoxy-phenyl)-quinazoline (CAS 885277-19-0)
- Methyl 2-(2-amino-5-fluorophenyl)acetate (CAS 29641-00-7)
- 5-Sulfamoyl-1H-indazole-3-carboxylic acid (CAS 1448314-67-7)
- N-benzyl-3-(trifluoromethyl)piperidin-3-amine (CAS 2306261-87-8)
- C-Peptide (Proinsulin) (CAS 59112-80-0)
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