3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoic acid CAS 438466-00-3
| CAS No. | 438466-00-3 |
| Molecular Formula | C11H10F4O3 |
| Molecular Weight | 266.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoic acid (CAS 438466-00-3), molecular formula C11H10F4O3 and molecular weight 266.19 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 3-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoic acid (C11H10F4O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 266.19 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H10F4O3 |
| Molecular Weight | 266.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related tetrafluoropropoxy Standards
- 4-[(2,2,3,3-tetrafluoropropoxy)methyl]benzoic acid (CAS 444151-68-2)
- Methyl 4-(2,2,3,3-tetrafluoropropoxy)benzoate (CAS 77598-65-3)
- 3-(4-(2,2,3,3-Tetrafluoropropoxy)phenyl)acrylonitrile (CAS 123632-23-5)
- 4-(2,2,3,3-Tetrafluoropropoxy)Phthalonitrile (CAS 121190-46-3)
- 6-(2,2,3,3-tetrafluoropropoxy)pyridine-3-carboxylic acid (CAS 223127-25-1)
- 3-(2,2,3,3-Tetrafluoropropoxy)benzoic acid (CAS 937602-64-7)
- 4-(2,2,3,3-Tetrafluoropropoxy)benzoic acid (CAS 72106-04-8)
- 3-((2,2,3,3-Tetrafluoropropoxy)methyl)benzohydrazide (CAS 438473-63-3)
Recommended Standards
- 2-methyl-7-(tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-indazole (CAS 845751-67-9)
- 3-Fluoro-4-isopropoxy-5-(trifluoromethyl)benzoic acid (CAS 2624417-09-8)
- 2-Fluoro-3-isopropoxy-5-(trifluoromethyl)benzoic acid (CAS 2432848-76-3)
- 3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine (CAS 2304634-64-6)
- 2-Methoxy-5-(piperidin-1-ylmethyl)aniline (CAS 1040061-69-5)
- 1-butylimidazolidine-2,4,5-trione (CAS 40408-40-0)
- Butyl 4-(2,4-dimethoxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 300799-47-7)
- 2-(2-Amino-5-cyclopropylphenyl)propan-2-ol (CAS 2844382-99-4)
- 4-chloro-1,6-dimethyl-1H-imidazo[4,5-c]pyridine (CAS 870135-17-4)
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