Methyl 6-(tert-butyl)-2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate CAS 438532-45-7
| CAS No. | 438532-45-7 |
| Molecular Formula | C18H21NO4S |
| Molecular Weight | 347.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 6-(tert-butyl)-2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate.
Methyl 6-(tert-butyl)-2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 438532-45-7), molecular formula C18H21NO4S and molecular weight 347.43 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Methyl 6-(tert-butyl)-2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (C18H21NO4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Methyl 6-(tert-butyl)-2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H21NO4S |
| Molecular Weight | 347.43 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Recommended Standards
- Methyl 4-((N-(3,4-dimethylphenyl)methylsulfonamido)methyl)benzoate (CAS 358377-75-0)
- Methyl N-(2,3-dimethylphenyl)-N-[(4-methylphenyl)sulfonyl]glycinate (CAS 446046-86-2)
- Ethyl 6-methyl-2-(5-methylfuran-2-carboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 315677-49-7)
- Methyl N-(2,4-dimethylphenyl)-N-tosylglycinate (CAS 425612-24-4)
- 4-(3,4-Dimethylphenoxy)-3-fluoroaniline (CAS 937597-99-4)
- Ethyl 1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-1h-pyrazole-3-carboxylate (CAS 1006336-63-5)
- 2-Chloro-N,N-dimethylacetamide (CAS 2675-89-0)
- 3-(4-Chlorophenyl)-1-(m-tolyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-49-1)
- 6-Methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carbaldehyde (CAS 2137691-14-4)
- 3-Methylbutane-1,3-diamine (CAS 116473-67-7)
- Methyl hexahydro-1H-pyrrolo[1,2-b]pyrazole-1-carboxylate (CAS 121643-92-3)
- N-(cyclopentylmethyl)-2,2-dimethoxyethan-1-amine (CAS 1248097-77-9)
- 3-Bromo-4-(1-piperidinylmethyl)pyridine (CAS 1449008-24-5)
- Semaglutide impurity 274 (CAS CATO-C4X-2226274)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com