2-Amino-N-(4-chlorophenyl)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamide CAS 438616-84-3
| CAS No. | 438616-84-3 |
| Molecular Formula | C16H17ClN2OS |
| Molecular Weight | 320.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Amino-N-(4-chlorophenyl)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamide.
2-Amino-N-(4-chlorophenyl)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamide (CAS 438616-84-3), molecular formula C16H17ClN2OS and molecular weight 320.84 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C16H17ClN2OS, 2-Amino-N-(4-chlorophenyl)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamide contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 320.84 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H17ClN2OS |
| Molecular Weight | 320.84 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 2-Amino-N-(2-chlorophenyl)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamide (CAS 312949-33-0)
- 2-Amino-N-(4-chlorophenyl)-6-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide (CAS 312948-96-2)
- N-(5-Amino-2-methoxyphenyl)-2-(4-chloro-3-methylphenoxy)acetamide (CAS 1020054-28-7)
- N-(5-Amino-2-methoxyphenyl)-2-(4-chloro-2-methylphenoxy)acetamide (CAS 1020054-43-6)
- N-(3-Amino-4-chlorophenyl)-2-(4-methoxyphenoxy)-propanamide (CAS 1020054-79-8)
- N-(3-Amino-4-chlorophenyl)-2-(2-methoxyphenoxy)-propanamide (CAS 1020054-82-3)
- N-(5-Amino-2-methoxyphenyl)-2-(4-chlorophenoxy)-propanamide (CAS 1020054-99-2)
- N-(5-Amino-2-methoxyphenyl)-2-(2-chlorophenoxy)-propanamide (CAS 1020055-19-9)
Recommended Standards
- 2-(Butylthio)-4-(2-chlorophenyl)-6-oxo-1,4,5,6-tetrahydropyridine-3-carbonitrile (CAS 375352-62-8)
- 4-[(4-Chlorophenyl)sulfanyl]-6-(piperidin-1-yl)pyrimidin-2-amine (CAS 339016-05-6)
- 1-{2-[(4-chlorophenyl)methyl]-1,3-thiazole-4-carbonyl}piperidine (CAS 478030-55-6)
- 4-Chloro-2-[(4-methylphenyl)methanesulfinyl]-5,6,7,8-tetrahydroquinazoline (CAS 477713-76-1)
- 3H-imidazo[4,5-b]pyridine-3-carboxylic acid, 6-bromo-, 1,1-dimethylethyl ester (CAS 1021919-30-1)
- 4-Chloro-6-fluoroquinoline-7-carbonitrile (CAS 1260824-76-7)
- Allyl isonicotinate (CAS 25635-24-9)
- Ascorbic Acid EP Impurity C (CAS 526-98-7)
- 2-{4-[(3-chlorophenyl)methyl]piperazin-1-yl}pyridine-3-carboxylic acid (CAS 1053960-15-8)
- 4-Fluorobenzyl Alcohol (CAS 459-56-3)
- 3,5-Difluoro-4-(trifluoromethoxy)benzonitrile (CAS 1805056-83-0)
- 5,5-Dimethyl-3-[(5-methylisoxazol-3-yl)amino]-cyclohex-2-en-1-one (CAS 897660-79-6)
- 6,8-Dibromo-3-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)-2-methylquinoline (CAS 861210-77-7)
- Semaglutide impurity 91 (CAS CATO-C4X-222691)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com