N-[6-(4-Methylpiperazin-1-yl)pyridin-3-yl]-4-(trifluoromethyl)benzamide CAS 439094-95-8
| CAS No. | 439094-95-8 |
| Molecular Formula | C18H19F3N4O |
| Molecular Weight | 364.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of N-[6-(4-Methylpiperazin-1-yl)pyridin-3-yl]-4-(trifluoromethyl)benzamide (C18H19F3N4O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
N-[6-(4-Methylpiperazin-1-yl)pyridin-3-yl]-4-(trifluoromethyl)benzamide (CAS 439094-95-8), molecular formula C18H19F3N4O and molecular weight 364.36 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures N-[6-(4-Methylpiperazin-1-yl)pyridin-3-yl]-4-(trifluoromethyl)benzamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H19F3N4O |
| Molecular Weight | 364.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related N Standards
- N-(4-Methylpiperazin-1-yl)-1-(3-(3-nitrophenyl)imidazo[1,5-a]pyridin-1-yl)methanimine (CAS 618859-69-1)
- 7-(2-(4-Methylpiperazin-1-yl)ethoxy)-3-phenyl-4H-chromen-4-one (CAS 287472-17-7)
- 8-Ethyl-2-[[4-(4-methylpiperazin-1-yl)phenyl]amino]-8H-pyrido[2,3-d]pyrimidin-7-one (CAS 211245-14-6)
- N-(2-(4-methylpiperazin-1-yl)phenyl)-3-(trifluoromethyl)benzamide (CAS 400076-90-6)
- n-(4-(4-Methylpiperazin-1-yl)phenyl)-3-(trifluoromethyl)benzamide (CAS 303150-62-1)
- 4-(4-(4-Methylpiperazin-1-yl)-3-nitrophenyl)phthalazin-1-ol (CAS 797766-21-3)
- 898762-15-7 {2-[(4-Methylpiperazin-1-yl)methyl]phenyl}[4-(trifluoromethyl)phenyl]methanone DTXSID90643889 (CAS 898762-15-7)
- Ethyl 4-(2-((4-methylpiperazin-1-yl)methyl)benzoyl)benzoate (CAS 898782-95-1)
Recommended Standards
- ethyl 2-[(tert-butylthio)methyl]-4,5,6,7-tetrafluorobenzo[b]furan-3-carboxylate (CAS 256425-14-6)
- tert-Butyl (12-bromododecyl)carbamate (CAS 887353-35-7)
- benzyl (4-(4,4-difluoropiperidin-1-yl)-3-fluorophenyl)carbamate (CAS 2102410-40-0)
- Boceprevir impurity 23 (CAS 2755812-45-2)
- tert-butyl (R)-3-(methylamino)pyrrolidine-1-carboxylate (CAS 147081-59-2)
- (R)-5-(4-fluorophenyl)pyrrolidin-2-one (CAS 890853-47-1)
- 2-(6-Chloro-2,2-difluorobenzo[d][1,3]dioxol-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1628572-71-3)
- 1,2,4-Trimethyl-1H-pyrrole (CAS 931-25-9)
- 1-(Tert-butyl) 2-methyl (2R,4R)-4-(benzyloxy)pyrrolidine-1,2-dicarboxylate (CAS 250122-38-4)
- 1-Methylnaphthalene-7-acetic acid (CAS 1261471-03-7)
- (5-Fluoro-2-methoxyphenyl)trimethylsilane (CAS 708-50-9)
- Aprepitant Impurity 69 (CAS 178616-88-1)
- 2,2-Dimethyl-1-(pyridin-3-yl)pent-4-en-1-ol (CAS 864684-91-3)
- Semaglutide impurity 81 (CAS CATO-C4X-222681)
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