4-(2-Fluorophenyl)-2-(methylthio)-1,4-dihydro-5H-indeno[1,2-d]pyrimidin-5-one CAS 439095-11-1
| CAS No. | 439095-11-1 |
| Molecular Formula | C18H13FN2OS |
| Molecular Weight | 324.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(2-Fluorophenyl)-2-(methylthio)-1,4-dihydro-5H-indeno[1,2-d]pyrimidin-5-one.
4-(2-Fluorophenyl)-2-(methylthio)-1,4-dihydro-5H-indeno[1,2-d]pyrimidin-5-one (CAS 439095-11-1) is a high-purity analytical reference standard with the molecular formula C18H13FN2OS and a molecular weight of 324.37 g/mol.
The molecular framework of 4-(2-Fluorophenyl)-2-(methylthio)-1,4-dihydro-5H-indeno[1,2-d]pyrimidin-5-one (C18H13FN2OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(2-Fluorophenyl)-2-(methylthio)-1,4-dihydro-5H-indeno[1,2-d]pyrimidin-5-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H13FN2OS |
| Molecular Weight | 324.37 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Fluorophenyl Standards
- [(2-Fluorophenyl)methyl]({[(4-methoxyphenyl)methyl]sulfamoyl})amine (CAS 337924-22-8)
- 4-(4-Fluorophenyl)-5-hydroxymethyl-6-isopropyl-2-methylsulfonylpyrimidine 4-(4-Fluorophenyl)-6-(1-methylethyl)-2-(methylsulfonyl)-5-pyrimidinemethanol 849470-59-3 (CAS 849470-59-3)
- 1-(4-Fluorophenyl)-4-(1-phenyl-1h-tetrazol-5-yl)piperazine (CAS 339105-28-1)
- 2-(3-Fluorophenyl)-5-((4-methylpiperidin-1-yl)methyl)benzo[d]oxazole (CAS 1706443-79-9)
- 2-(3-Fluorophenyl)-5-((3-methylpiperidin-1-yl)methyl)benzo[d]oxazole (CAS 1706449-67-3)
- 2-(4-Fluorophenyl)-4-(piperidin-1-yl)pyrazolo[1,5-a]pyrazine-3-carbaldehyde (CAS 1707668-16-3)
- 2-(3-Fluorophenyl)-4-(piperidin-1-yl)pyrazolo[1,5-a]pyrazine-3-carbaldehyde (CAS 1713590-35-2)
- (2E)-1-[4-(4-Fluorophenyl)piperazin-1-yl]-3-(3-methylphenyl)prop-2-en-1-one (CAS 329779-87-5)
Recommended Standards
- 4-(1-Cyclohexyl-6-hydroxy-1H-indazol-3-yl)benzene-1,3-diol (CAS 680610-79-1)
- 4-(3-Hydroxybutyl)-1,2-diphenylpyrazolidine-3,5-dione (CAS 568-76-3)
- 4-((6,7-Dimethoxyquinolin-4-yl)oxy)-2,5-dimethylaniline (CAS 286371-46-8)
- 4-Butyl-5-hydroxy-2-(4-hydroxyphenyl)-1-phenyl-1H-pyrazol-3(2H)-one (CAS 975-18-8)
- 3-{[2-(Trifluoromethyl)phenoxy]methyl}piperidinehydrochloride (CAS 1219960-58-3)
- 2-(chloromethyl)-4-methoxy-6-methylpyridine hydrochloride (CAS 110374-34-0)
- (4-Methyloxazol-5-yl)(phenyl)methanone (CAS 162818-61-3)
- 3-(2,4-Dichloro-6-methylphenyl)-1,1-diisopropylthiourea (CAS 1980044-24-3)
- 2-Isobutyl-4-phenylphthalazin-1(2H)-one (CAS 329066-79-7)
- 8-Methyl-2,6-dioxa-9-azaspiro[4.5]Decane (CAS 1553622-23-3)
- 3-(Adamantan-1-yl)propan-1-amine hydrochloride (CAS 31897-98-0)
- Ethyl 3-(1,3-dioxo-2,3-dihydro-1H-inden-2-ylidene)-4,6-dioxo-5-[3-(trifluoromethyl)phenyl]-octahydropyrrolo[3,4-c]pyrrole-1-carboxylate (CAS 321522-10-5)
- 2-(5-Carbamoyl-1H-pyrazol-1-yl)ethyl formate (CAS 1260764-30-4)
- Fragment-[3-31]-Liraglutide (CAS CATO-C4X-199232)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com