5-(3-Chlorophenyl)-3-(4-fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine CAS 439096-17-0
| CAS No. | 439096-17-0 |
| Molecular Formula | C19H10ClF4N3 |
| Molecular Weight | 391.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(3-Chlorophenyl)-3-(4-fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine.
CATO supplies 5-(3-Chlorophenyl)-3-(4-fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (CAS 439096-17-0), a certified reference material (molecular formula C19H10ClF4N3, MW 391.75 g/mol) for analytical method development and quality control.
Structurally, 5-(3-Chlorophenyl)-3-(4-fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (C19H10ClF4N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 391.75 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(3-Chlorophenyl)-3-(4-fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H10ClF4N3 |
| Molecular Weight | 391.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorophenyl Standards
- N-(3-Chlorophenyl)-1,1,1-trifluoro-N-((trifluoromethyl)sulfonyl)methanesulfonamide (CAS 1092576-42-5)
- N-(2-Chlorophenyl)-1,1,1-trifluoro-N-((trifluoromethyl)sulfonyl)methanesulfonamide (CAS 1263377-02-1)
- 2-[(3-Chlorophenyl)sulfanyl]-6-(3,4-dichlorophenyl)pyridine-3-carbonitrile (CAS 252059-67-9)
- 2-[(4-Chlorophenyl)sulfanyl]-6-(3,4-dichlorophenyl)pyridine-3-carbonitrile (CAS 252059-64-6)
- 5-(4-Chlorophenyl)-2-[(2,6-dichlorophenyl)sulfanyl]pyridine-3-carbonitrile (CAS 338955-21-8)
- N-(4-chlorophenyl)-1,1,1-trifluoro-N-((trifluoromethyl)sulfonyl)methanesulfonamide (CAS 950578-84-4)
- N-(4-chlorophenyl)-5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-amine (CAS 241488-35-7)
- 2-(4-Chlorophenyl)-4-methyl-6-(2-phenylpyrimidin-4-yl)-1,2,4-triazine-3,5(2H,4H)-dione (CAS 477854-28-7)
Recommended Standards
- Naphthol AS-TR phosphate (CAS 2616-72-0)
- Dotinurad Impurity 109 (CAS 1285572-82-8)
- Ethyl 3-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)(methyl)amino)-2,4-dioxo-3-azabicyclo[3.1.0]Hexane-6-carboxylate (CAS 318237-93-3)
- (R)-Carisbamate beta-D-O-Glucuronide (CAS 940279-83-4)
- 2-Benzyl-4-bromo-1-methoxybenzene (CAS 41876-52-2)
- 7-Bromopyrido[2,3-b]pyrazine-8-carbaldehyde (CAS 893566-36-4)
- 2-Cyclohexyl-5,6-dimethyl-4-piperazin-1-yl-thieno[2,3-d]pyrimidine (CAS 1361118-58-2)
- tert-Butyl (3-chloro-4-methylphenyl)carbamate (CAS 100282-49-3)
- Nitroso Perindopril EP impurity Y (CAS CATO-C4X-125262)
- 4-Bromo-2,5-dimethyl-N-(pyridin-3-yl)benzenesulfonamide (CAS 898654-26-7)
- (±)-Tonalide-d3 (acetyl-d3) (CAS 1396967-82-0)
- Triphenylphosphinepentacarbonylchromium (CAS 14917-12-5)
- 4-Piperidinylmethyl 4-chloro-2-pyridinecarboxylate hydrochloride (CAS 1220020-89-2)
- D-Ala18-Tirzepatide (CAS CATO-CPTD788916)
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