2-Hydroxy-6-(3-methoxyphenyl)-4-(trifluoromethyl)nicotinonitrile CAS 439097-24-2
| CAS No. | 439097-24-2 |
| Molecular Formula | C14H9F3N2O2 |
| Molecular Weight | 294.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Hydroxy-6-(3-methoxyphenyl)-4-(trifluoromethyl)nicotinonitrile.
CATO supplies 2-Hydroxy-6-(3-methoxyphenyl)-4-(trifluoromethyl)nicotinonitrile (CAS 439097-24-2), a certified reference material (molecular formula C14H9F3N2O2, MW 294.23 g/mol) for analytical method development and quality control.
2-Hydroxy-6-(3-methoxyphenyl)-4-(trifluoromethyl)nicotinonitrile (C14H9F3N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H9F3N2O2 |
| Molecular Weight | 294.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Hydroxy Standards
- 2-Hydroxy-5-((3-(trifluoromethyl)phenyl)diazenyl)benzaldehyde (CAS 221296-60-2)
- 2-Hydroxy-7-methoxy-2-(1,1,2,2-tetrafluoroethyl)chroman-4-one (CAS 337467-33-1)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (3-cyclohexylfuran-2-yl)boronate (CAS 2223031-92-1)
- n-Hydroxy-4-nitro-n-phenylbenzenesulfonamide (CAS 32234-31-4)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (4-(1H-imidazol-1-yl)thiophen-2-yl)boronate (CAS 2223032-27-5)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (4-(1H-pyrazol-1-yl)thiophen-2-yl)boronate (CAS 2223029-59-0)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-(1H-imidazol-1-yl)thiophen-2-yl)boronate (CAS 2223051-07-6)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-(1H-pyrazol-1-yl)thiophen-2-yl)boronate (CAS 2223032-96-8)
Recommended Standards
- 3-(3,4,5-Trifluorobenzoyl)phenyl acetate (CAS 890099-23-7)
- 2-Acetoxy-3,4,5-trifluorobenzophenone (CAS 890099-18-0)
- 3-(4-Methoxyphenyl)-6-(trifluoromethyl)-[1,2]oxazolo[4,3-b]pyridine (CAS 339097-16-4)
- 2,2-Difluoro-1-phenylethyl diethyl phosphate (CAS 83567-91-3)
- N-(Piperidin-4-yl)quinazolin-4-amine (CAS 1183120-04-8)
- 2-(3,4-Dichlorophenyl)-2-{4h,5h,6h,7h-thieno[3,2-c]pyridin-5-yl}ethan-1-amine (CAS 1041546-96-6)
- Methyl 2,4,5-trimethylbenzoate (CAS 51664-96-1)
- Sarpogrelate Impurity 21 (CAS CATO-C4X-291321)
- 1-((2,4-Dichlorophenoxy)methyl)-1h-pyrazole-3-carboxylic acid (CAS 1004193-04-7)
- 2-Propenoic acid, 2-methyl-, polymer with 2,3-dibromopropyl 2-propenoate and methyl 2-methyl-2-propenoate (CAS 52664-82-1)
- 5-Phenyl-3-(3-(trifluoromethyl)phenyl)pyridazin-4(1H)-one (CAS 59591-39-8)
- Di-furan-2-yl-methanone (CAS 17920-86-4)
- 3,4-Dichloro-2-(difluoromethyl)quinoline (CAS 1707603-52-8)
- 3AEEA-Semaglutide(Endo-AEEA-Semaglutide) (CAS CATO-C4X-2226265)
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