1-{2-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]thiophen-3-yl}-1H-pyrrole CAS 439109-43-0
| CAS No. | 439109-43-0 |
| Molecular Formula | C16H11F3N4S |
| Molecular Weight | 348.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-{2-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]thiophen-3-yl}-1H-pyrrole.
1-{2-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]thiophen-3-yl}-1H-pyrrole (CAS 439109-43-0) is a high-purity analytical reference standard with the molecular formula C16H11F3N4S and a molecular weight of 348.35 g/mol.
The molecular framework of 1-{2-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]thiophen-3-yl}-1H-pyrrole (C16H11F3N4S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-{2-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]thiophen-3-yl}-1H-pyrrole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H11F3N4S |
| Molecular Weight | 348.35 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related methyl Standards
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Recommended Standards
- 1,4-Phenylene bis(4-aminobenzoate) (CAS 22095-98-3)
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- 1,3-Dioxoisoindolin-2-yl 2-((tert-butoxycarbonyl)amino)-2-methylpropanoate (CAS 2240185-68-4)
- 2-([1,1'-Biphenyl]-4-yl)-2-oxoethyl 2,4-dihydroxybenzoate (CAS 923147-08-4)
- 4-(Isopropylsulfonyl)benzene-1-sulfonyl chloride (CAS 1540528-87-7)
- Atrial Natriuretic Peptide (ANP)(1-28) Alpha (Human, Ovine, Canine) (CAS 91917-63-4)
- 5-((2-Chloro-5-methylphenoxy)methyl)furan-2-carbohydrazide (CAS 832737-50-5)
- 5-(4-tert-Butyl-phenyl)-5-methyl-imidazolidine-2,4-dione (CAS 61344-30-7)
- 1-Ethyl-5-(trifluoromethyl)-1h-pyrazole-4-carboxylic acid (CAS 1235439-80-1)
- 6-Chloro-1H-indole-2,3-dione 3-oxime (CAS 117886-84-7)
- (4-Fluorophenyl)(2-methylpiperidin-1-yl)methanone (CAS 330469-30-2)
- 4-(tert-Pentyl)cyclohexanone (CAS 16587-71-6)
- Ethyl 2-(4-fluorophenyl)pyrazolo[1,5-a]pyridine-3-carboxylate (CAS 1426521-37-0)
- Des-Ala35-Tirzepatide (CAS CATO-CPTD788939)
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