2-Amino-3-(2-fluoro-4-(trifluoromethyl)phenyl)propanoic acid CAS 439587-15-2
| CAS No. | 439587-15-2 |
| Molecular Formula | C10H9F4NO2 |
| Molecular Weight | 251.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Amino-3-(2-fluoro-4-(trifluoromethyl)phenyl)propanoic acid.
2-Amino-3-(2-fluoro-4-(trifluoromethyl)phenyl)propanoic acid (CAS 439587-15-2), molecular formula C10H9F4NO2 and molecular weight 251.18 g/mol, is a CATO reference standard with documented purity and traceability.
2-Amino-3-(2-fluoro-4-(trifluoromethyl)phenyl)propanoic acid (C10H9F4NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Amino-3-(2-fluoro-4-(trifluoromethyl)phenyl)propanoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H9F4NO2 |
| Molecular Weight | 251.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Amino Standards
- 2-Amino-3-(2-fluoro-6-(trifluoromethyl)phenyl)propanoic acid (CAS 1043500-58-8)
- 2-Amino-3-(3-fluoro-4-(trifluoromethyl)phenyl)propanoic acid (CAS 1215491-31-8)
- 2-Amino-3-(3-fluoro-2-(trifluoromethyl)phenyl)propanoic acid (CAS 1256482-60-6)
- 2-Amino-3-(3-fluoro-5-(trifluoromethyl)phenyl)propanoic acid (CAS 1259992-93-2)
- 2-Amino-3-(2-fluoro-3-(trifluoromethyl)phenyl)propanoic acid (CAS 1259993-82-2)
- 2-Amino-3-(2-fluoro-5-(trifluoromethyl)phenyl)propanoic acid (CAS 1259994-87-0)
- 2-Amino-3-(4-fluoro-2-(trifluoromethyl)phenyl)propanoic acid (CAS 1259997-93-7)
- 2-Amino-3-(5-fluoro-2-(trifluoromethyl)phenyl)propanoic acid (CAS 1260002-41-2)
Recommended Standards
- Ethyl 3-fluoro-6-(trifluoromethyl)pyridine-2-acetate (CAS 1806313-72-3)
- 2-Fluoro-N-methoxy-N-methyl-3-(trifluoromethyl)benzamide (CAS 680610-54-2)
- 9,9-Dichloro-9-silafluorene (CAS 18030-58-5)
- 2-Fluoro-N-methoxy-N-methyl-4-(trifluoromethyl)benzamide (CAS 198967-27-0)
- Ethyl 2-methyl-3-oxo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-2-carboxylate (CAS 154365-38-5)
- 6-(Methylsulfonyl)-3-nitroimidazo[1,2-b]pyridazine (CAS 56023-65-5)
- 4-Chloro-2-ethylbenzaldehyde (CAS 1043500-82-8)
- 1-Bromo-2-fluoro-4-iodo-3-methoxybenzene (CAS 1824571-99-4)
- 5-(Benzo[d]oxazol-2-yl)-1H-1,2,4-triazol-3(2H)-one (CAS 78620-35-6)
- Lithium (5-fluoropyridin-2-yl)trihydroxyborate (CAS 1393822-88-2)
- 3-[4-(2-Fluorophenyl)piperazine-1-carbonyl]-5-methyl-5H,5aH,6H,7H,8H,9H,11H-pyrido[2,1-b]quinazolin-11-one (CAS 1574576-94-5)
- Muraglitazar acyl-β-D-glucuronide (CAS 875430-26-5)
- 2-(4-Acetoxyphenyl)pyrimidine-5-carboxylic acid (CAS 142603-91-6)
- Semaglutide impurity 196 (CAS CATO-C4X-2226196)
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