2-(4-Fluoro-phenyl)-quinoline-4-carboxylic acid CAS 441-28-1
| CAS No. | 441-28-1 |
| Molecular Formula | C16H10FNO2 |
| Molecular Weight | 267.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-(4-Fluoro-phenyl)-quinoline-4-carboxylic acid (CAS 441-28-1), molecular formula C16H10FNO2 and molecular weight 267.25 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-(4-Fluoro-phenyl)-quinoline-4-carboxylic acid (C16H10FNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 267.25 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 2-(4-Fluoro-phenyl)-quinoline-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H10FNO2 |
| Molecular Weight | 267.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
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Recommended Standards
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- 2-(3-Fluorophenyl)-4-quinolinecarboxylic acid (CAS 883524-80-9)
- 2,5-Dimethyl-1-(4-(trifluoromethyl)phenyl)-1h-pyrrole-3-carbaldehyde (CAS 256529-25-6)
- 1-Bromo-2-((2-isopropoxyphenoxy)methyl)benzene (CAS 1309933-47-8)
- 3-Chloro-o-anisidine 3-chloro-2-methoxyaniline 51114-68-2 (CAS 51114-68-2)
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