1-(1,3-Dioxolan-2-ylmethyl)-4-methylbenzene CAS 4412-50-4

Purity 97%+In StockPharmaceutical Standards
CAS No.4412-50-4
Molecular FormulaC11H14O2
Molecular Weight178.23 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(1,3-Dioxolan-2-ylmethyl)-4-methylbenzene CAS 4412-50-4 chemical structure

Description

The occurrence of 1-(1,3-Dioxolan-2-ylmethyl)-4-methylbenzene is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 1-(1,3-Dioxolan-2-ylmethyl)-4-methylbenzene (CAS 4412-50-4), a certified reference material (molecular formula C11H14O2, MW 178.23 g/mol) for analytical method development and quality control.

The molecular framework of 1-(1,3-Dioxolan-2-ylmethyl)-4-methylbenzene (C11H14O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H14O2
Molecular Weight178.23 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at 2-8°C
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1958

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