methyl (E)-3-(4-(((2-(2-methyl-1H-indol-3-yl)ethyl)amino)methyl)phenyl)acrylate CAS 441741-66-8
| CAS No. | 441741-66-8 |
| Molecular Formula | C22H24N2O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of methyl (E)-3-(4-(((2-(2-methyl-1H-indol-3-yl)ethyl)amino)methyl)phenyl)acrylate (C22H24N2O2HCl) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
methyl (E)-3-(4-(((2-(2-methyl-1H-indol-3-yl)ethyl)amino)methyl)phenyl)acrylate (CAS 441741-66-8), molecular formula C22H24N2O2HCl and molecular weight 384.90 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H24N2O2 HCl |
| Molecular Weight | 384.90 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- Tert-butyl 6-oxa-2-azaspiro[4.5]Decane-2-carboxylate (CAS 2206114-57-8)
- N-(5-Amino-2-methylphenyl)-2-[2-(sec-butyl)-phenoxy]propanamide (CAS 1020054-87-8)
- 6-Amino-5-methoxy-1H-indole-2-carboxylic acid (CAS 139121-47-4)
- (4,5-Difluoro-2-hydroxyphenyl)(phenyl)methanone (CAS 1372178-15-8)
- 3-(2-(1,3-Dioxolan-2-yl)ethyl)-2-methylbenzo[d]thiazol-3-ium iodide (CAS 2347569-99-5)
- 4-Hydroxy-N-methyl-1H-imidazole-5-carboxamide (CAS 67218-77-3)
- (2E)-3-{4-Methoxy-3-[(3-nitro-1H-pyrazol-1-yl)-methyl]phenyl}acrylic acid 1173471-09-4 9936AC C14H13N3O5 (CAS 1173471-09-4)
- 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-7-phenyl-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 338775-17-0)
- Carbocisteine Impurity 14 (CAS CATO-C4X-201014)
- (D-Ala1)-Peptide T amide (CAS 106362-34-9)
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