2',7'-Dibromospiro[cyclopentane-1,9'-fluorene] CAS 441771-49-9
| CAS No. | 441771-49-9 |
| Molecular Formula | C17H14Br2 |
| Molecular Weight | 378.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2',7'-Dibromospiro[cyclopentane-1,9'-fluorene] (CAS 441771-49-9) is a high-purity analytical reference standard with the molecular formula C17H14Br2 and a molecular weight of 378.10 g/mol.
The molecular framework of 2',7'-Dibromospiro[cyclopentane-1,9'-fluorene] (C17H14Br2) is characterized by bromine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H14Br2 |
| Molecular Weight | 378.10 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
Related Dibromospiro Standards
- 2',6'-Dibromospiro[cyclopentane-1,9'-fluorene] (CAS 925890-09-1)
- 2’,7’-Dibromospiro[cyclopent[3]ene-1,9’-fluorene] (CAS 951884-04-1)
- 2',6'-Dibromospiro[cyclohexane-1,9'-fluorene] (CAS 925890-05-7)
- 2',7'-Dibromospiro[cyclohexane-1,9'-fluorene] (CAS 736138-41-3)
- 2,7-Dibromospiro[fluorene-9,4'-piperidine] (CAS 1616113-97-3)
- 2,6-Dibromospiro[cyclopenta[2,1-b:3,4-b']dithiophene-4,2'-[1,3]dioxolane] (CAS 771579-00-1)
- 1',4'-Dibromospiro[1,3-dioxolane-2,10'-tricyclo[5.2.1.0,2,6]decane]-3',8'-dien-5'-one (CAS 95272-45-0)
- 2,7-Dibromospiro[fluorene-9,2'-[1,3]dithiolane] (CAS 113425-39-1)
Recommended Standards
- Ambroxol Impurity 35 (CAS 36557-04-7)
- 2,6-Dibromo-4-(3-(tert-butyl)oxazolidin-5-yl)aniline (CAS 88698-33-3)
- Ambroxol (CAS 18683-91-5)
- Ambroxol EP Impurity D (CAS 107814-37-9)
- 1-Ethynyl-4-methyl-2-nitrobenzene (CAS 875768-16-4)
- 5-Chloro-3-((trimethylsilyl)ethynyl)pyridin-2-amine (CAS 866318-90-3)
- 1-(2-Fluorophenyl)cyclopentanemethanamine (CAS 378247-87-1)
- (1R,2S)-1-iodo-2-(perfluoroethyl)cyclohexane (CAS 38787-67-6)
- (R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(3,5-dimethoxyphenyl)propanoic acid (CAS 2015414-19-2)
- 2-(4-Aminopyridin-2-yl)acetonitrile (CAS 415912-70-8)
- 1-(6-Nitro-2,3-dihydro-4H-benzo[b][1,4]oxazin-4-yl)ethan-1-one (CAS 120711-96-8)
- 6-Benzylpicolinonitrile (CAS 139478-84-5)
- tert-Butyl 2-oxo-1-azaspiro[3.5]nonane-1-carboxylate (CAS 204132-39-8)
- Tau Peptide (245-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 1428134-39-7)
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