1-isocyanato-4-methanesulfonylbenzene CAS 4418-85-3
| CAS No. | 4418-85-3 |
| Molecular Formula | C8H7NO3S |
| Molecular Weight | 197.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-isocyanato-4-methanesulfonylbenzene.
1-isocyanato-4-methanesulfonylbenzene (CAS 4418-85-3), molecular formula C8H7NO3S and molecular weight 197.21 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-isocyanato-4-methanesulfonylbenzene (C8H7NO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-isocyanato-4-methanesulfonylbenzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H7NO3S |
| Molecular Weight | 197.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related isocyanato Standards
- 1-Isocyanato-2-(methylsulfonyl)benzene (CAS 167951-56-6)
- Methyl 2-isocyanato-5-methylthiophene-3-carboxylate (CAS 956576-57-1)
- 2-ethyl-4-isocyanato-benzoate 2-ethyl-4-isocyanatobenzoate 30806-83-8 A820631 (CAS 30806-83-8)
- 4-Isocyanato-2,2,6,6-tetramethyl-1-piperidinyloxy 4-Isocyanato-TEMPO, Technical grade (approximately 85%) 88418-69-3 (CAS 88418-69-3)
- 4-Isocyanato-2-phenylpyridine (CAS 1260664-31-0)
- 2-isocyanato-1,1'-biphenyl (CAS 17337-13-2)
- 1-Isocyanato-2-methoxynaphthalene (CAS 117202-73-0)
- 3-Isocyanato-2-methyl-5-phenyl-furan (CAS 568577-82-2)
Recommended Standards
- 1H-pyrrolo[3,2-c]pyridine-1-sulfonamide (CAS 2387598-15-2)
- 1-tert-Butyl-2-fluoro-4-nitrobenzene (CAS 489-18-9)
- 1H-pyrrolo[3,2-b]pyridine-1-sulfonamide (CAS 2172947-76-9)
- 2-((2-Fluorophenyl)amino)-2-methylpropanoic acid (CAS 725234-47-9)
- 4-Chloro-2-(4-methoxyphenyl)-5-methylquinazoline (CAS 885277-29-2)
- 4-Chloro-3-methylphenol (CAS 15733-22-9)
- 2-Chloro-5-(Fluoromethyl)Pyridine (CAS 253686-24-7)
- 5-Amino-2-fluorobenzyl bromide (CAS 518057-73-3)
- (3aS,4R,6S,6aS)-6-Methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole-4-carbaldehyde (CAS 1253592-01-6)
- (S)-2-(tetrahydrofuran-2-yl)acetic acid (CAS 1240504-10-2)
- (1-Amino-3-(4-hydroxyphenyl)propan-2-yl)phosphonic acid (CAS 66794-15-8)
- 1-(3-Fluoro-4-(trifluoromethoxy)phenyl)ethan-1-one (CAS 1174006-08-6)
- 6'-Chlorospiro[cyclobutane-1,3'-indoline] (CAS 1403899-03-5)
- Semaglutide impurity 33 (CAS CATO-C4X-222633)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com