2H-Spiro[benzofuran-3,4'-piperidin]-2-one CAS 4427-27-4

Purity 97%+In StockPharmaceutical Standards
CAS No.4427-27-4
Molecular FormulaC12H13NO2
Molecular Weight203.24 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2H-Spiro[benzofuran-3,4'-piperidin]-2-one CAS 4427-27-4 chemical structure

Description

The occurrence of 2H-Spiro[benzofuran-3,4'-piperidin]-2-one is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 2H-Spiro[benzofuran-3,4'-piperidin]-2-one (CAS 4427-27-4), a certified reference material (molecular formula C12H13NO2, MW 203.24 g/mol) for analytical method development and quality control.

The molecular framework of 2H-Spiro[benzofuran-3,4'-piperidin]-2-one (C12H13NO2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2H-Spiro[benzofuran-3,4'-piperidin]-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC12H13NO2
Molecular Weight203.24 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1958
Nitrogen Atoms1

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