1-(7-Amino-4,4-dimethyl-3,4-dihydroisoquinolin-2(1H)-yl)ethanone CAS 442846-63-1
| CAS No. | 442846-63-1 |
| Molecular Formula | C13H18N2O |
| Molecular Weight | 218.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-(7-Amino-4,4-dimethyl-3,4-dihydroisoquinolin-2(1H)-yl)ethanone (C13H18N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
1-(7-Amino-4,4-dimethyl-3,4-dihydroisoquinolin-2(1H)-yl)ethanone (CAS 442846-63-1) is a high-purity analytical reference standard with the molecular formula C13H18N2O and a molecular weight of 218.29 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(7-Amino-4,4-dimethyl-3,4-dihydroisoquinolin-2(1H)-yl)ethanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H18N2O |
| Molecular Weight | 218.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 1-(7-Amino-3,4-dihydroisoquinolin-2(1H)-yl)-2-methylpropan-1-one (CAS 1017674-92-8)
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Recommended Standards
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