6,7-Dimethoxy-1-((2-methoxyphenoxy)methyl)-N-(3-methoxyphenyl)-3,4-dihydroisoquinoline-2(1H)-carbothioamide CAS 443101-88-0
| CAS No. | 443101-88-0 |
| Molecular Formula | C27H30N2O5S |
| Molecular Weight | 494.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 494.60 g/mol gives 6,7-Dimethoxy-1-((2-methoxyphenoxy)methyl)-N-(3-methoxyphenyl)-3,4-dihydroisoquinoline-2(1H)-carbothioamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 6,7-Dimethoxy-1-((2-methoxyphenoxy)methyl)-N-(3-methoxyphenyl)-3,4-dihydroisoquinoline-2(1H)-carbothioamide (CAS 443101-88-0), a certified reference material (molecular formula C27H30N2O5S, MW 494.60 g/mol) for analytical method development and quality control.
Structurally, 6,7-Dimethoxy-1-((2-methoxyphenoxy)methyl)-N-(3-methoxyphenyl)-3,4-dihydroisoquinoline-2(1H)-carbothioamide (C27H30N2O5S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 494.60 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C27H30N2O5S |
| Molecular Weight | 494.60 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Dimethoxy Standards
- 2,3-Dimethoxy-5-iodo-N-((1-(4'-fluorobenzyl)-2-pyrrolidinyl)methyl)benzamide (CAS 124929-08-4)
- 2,2-Dimethoxy-2-phenylethanol (CAS 28203-05-6)
- 1-{3-[(6,7-Dimethoxy-1-methyl-3,4-dihydroisoquinolin-2(1H)-yl)-methyl]-4-methoxyphenyl}-2,3,4,9-tetrahydro-1H-beta-carboline (CAS 312922-14-8)
- 6,7-Dimethoxy-3-(thiophen-2-ylmethyl)-2-((4-(trifluoromethyl)benzyl)thio)quinazolin-4(3H)-imine (CAS 691858-13-6)
- 3,4-Dimethoxy-N'-(2-(3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl)thiazole-4-carbonyl)benzenesulfonohydrazide (CAS 956782-90-4)
- 18,19-Dimethoxy-6-[1-methyl-5-(trifluoromethyl)-1H-pyrazol-4-yl]-4,5,9,13-tetraazapentacyclo[11.8.0.0^{3,11}.0^{4,8}.0^{16,21}]henicosa-3(11),5,7,9,16(21),17,19-heptaen-12-one (CAS 956755-40-1)
- 1-(4-((6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl)phenyl)-3-(4-(trifluoromethoxy)phenyl)urea (CAS 1023493-40-4)
- 1-(4-((6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl)phenyl)-3-(2-(trifluoromethoxy)phenyl)urea (CAS 1024431-81-9)
Recommended Standards
- Methyl (2S,3S,4S,5R,6S)-4,5-bis(benzyloxy)-3-hydroxy-6-(p-tolylthio)tetrahydro-2H-pyran-2-carboxylate (CAS 1352561-81-9)
- m-PEG7-Tos (CAS 79622-11-0)
- 2-((2-(4-(4-Fluorophenyl)piperazin-1-yl)-2-oxoethyl)thio)-3-methyl-7-phenylthieno[3,2-d]pyrimidin-4(3H)-one (CAS 1040632-23-2)
- Propargyl-peg3-sulfone-peg3-propargyl (CAS 2055024-44-5)
- 1-(3-Methylisoxazol-5-yl)methanamine (CAS 154016-55-4)
- 1,7-dioxaspiro[3.5]nonan-3-amine (CAS 2306260-74-0)
- Paxalisib-D8 (CAS 1382979-44-3)
- N-Methyl-N-(3-pyrrolidinylmethyl)-1-butanaminedihydrochloride (CAS 1219964-16-5)
- Di-Boc-L-cystathionine (CAS 64905-03-9)
- 3-[(1,2,3,4-tetrahydroisoquinolin-2-yl)carbonylamino]propanoic acid (CAS 1017667-47-8)
- N,N-bis(4-bromophenyl)-9,9-dimethyl-9H-fluoren-2-amine (CAS 1216940-51-0)
- Ethyl 2-oxotetrahydrofuran-3-carboxylate (CAS 77513-58-7)
- 2-Butylthiazole-5-carboxylic acid (CAS 30709-73-0)
- (Des-Gly2)-Exenatide trifluoroacetate salt (CAS 1678416-78-8)
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