6-Bromo-2-nitropyridin-3-ol CAS 443956-08-9
| CAS No. | 443956-08-9 |
| Molecular Formula | C5H3BrN2O3 |
| Molecular Weight | 218.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Bromo-2-nitropyridin-3-ol.
6-Bromo-2-nitropyridin-3-ol (CAS 443956-08-9) is a high-purity analytical reference standard with the molecular formula C5H3BrN2O3 and a molecular weight of 218.99 g/mol.
Based on its molecular formula C5H3BrN2O3, 6-Bromo-2-nitropyridin-3-ol contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 218.99 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-Bromo-2-nitropyridin-3-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H3BrN2O3 |
| Molecular Weight | 218.99 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 2-Bromo-4-nitropyridin-3-ol (CAS 1013642-97-1)
- 3-Bromo-2-oxo-2H-pyran-5-carboxylic acid (CAS 108723-62-2)
- 6-Bromo-3-hydroxypyrazine-2-carboxylic acid (CAS 1260667-67-1)
- 5-Bromo-6-hydroxypyrimidine-4-carboxylic acid (CAS 135274-82-7)
- 3-Bromo-2-hydroxy-5-nitropyridine (CAS 15862-33-6)
- 2-Bromo-6-nitropyridin-3-ol (CAS 167683-72-9)
- 3-Bromo-4-nitropyridine 1-Oxide (CAS 1678-49-5)
- 5-Bromo-6-oxo-1,6-dihydropyridazine-3-carboxylic acid (CAS 1781856-45-8)
Recommended Standards
- 5-bromo-4-oxo-4H-pyran-2-carboxylic acid (CAS 67897-52-3)
- 6-Bromo-5-nitropyridin-2-ol (CAS 623563-76-8)
- 5-Bromo-3-hydroxy-2-nitropyridine (CAS 691872-15-8)
- (1-(Methoxycarbonyl)-1H-indol-2-yl)boronic acid (CAS 1001162-89-5)
- 2,5-Dimethylphenyl 2,5-dimethoxybenzenesulfonate (CAS 433695-44-4)
- Methyl 5-Ethyl-2-pyridine-carboxylate (CAS 13509-14-3)
- 3-(4-formylpiperazin-1-yl)-3-oxopropanenitrile (CAS 733030-87-0)
- 5-epi-Emtricitabine Hydrochloride (CAS 483299-09-8)
- 4-Hydroxypyrrolidine-3-carboxylic acid (CAS 1314929-86-6)
- 2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl)-propionic acid (CAS 876709-28-3)
- 2-(methylsulfanyl)[1,3]thiazolo[4,5-c]pyridine (CAS 65128-67-8)
- 1-Iodoperfluoro-1-methylcyclopentane (CAS 125112-67-6)
- 1-Azaspiro[4.4]Nonan-4-ol (CAS 1553896-22-2)
- Semaglutide Impurity 192 (CAS CATO-C4X-2226192)
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