1,3-Dibromo-2-fluoro-5-methylbenzene CAS 444-13-3

Purity 97%+In StockPharmaceutical Standards
CAS No.444-13-3
Molecular FormulaC7H5Br2F
Molecular Weight267.92 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1,3-Dibromo-2-fluoro-5-methylbenzene CAS 444-13-3 chemical structure

Description

The occurrence of 1,3-Dibromo-2-fluoro-5-methylbenzene is closely related to fluorine/bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 1,3-Dibromo-2-fluoro-5-methylbenzene (CAS 444-13-3), a certified reference material (molecular formula C7H5Br2F, MW 267.92 g/mol) for analytical method development and quality control.

The molecular framework of 1,3-Dibromo-2-fluoro-5-methylbenzene (C7H5Br2F) is characterized by fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC7H5Br2F
Molecular Weight267.92 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentF/Br-containing

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