1-(2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-5-ethyl-4-(1-(phenylsulfonyl)ethyl)-1,3-dihydro-2H-imidazol-2-one CAS 444151-76-2
| CAS No. | 444151-76-2 |
| Molecular Formula | C21H22ClF3N4O3S |
| Molecular Weight | 502.94 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-(2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-5-ethyl-4-(1-(phenylsulfonyl)ethyl)-1,3-dihydro-2H-imidazol-2-one (C21H22ClF3N4O3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
1-(2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-5-ethyl-4-(1-(phenylsulfonyl)ethyl)-1,3-dihydro-2H-imidazol-2-one (CAS 444151-76-2), molecular formula C21H22ClF3N4O3S and molecular weight 502.94 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-5-ethyl-4-(1-(phenylsulfonyl)ethyl)-1,3-dihydro-2H-imidazol-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H22ClF3N4O3S |
| Molecular Weight | 502.94 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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- 4-Chloro-N-{[4-(prop-2-en-1-yl)-5-({[4-(trifluoromethyl)phenyl]methyl}sulfanyl)-4H-1,2,4-triazol-3-yl]methyl}benzene-1-sulfonamide (CAS 338422-25-6)
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- N-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-2-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)acetamide (CAS 338409-44-2)
Recommended Standards
- {5-[(4-chlorophenyl)sulfanyl]-1-methyl-3-phenyl-1H-pyrazol-4-yl}methyl 3-(trifluoromethyl)benzoate (CAS 318289-02-0)
- 2-((5-(4-Chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-(trifluoromethyl)phenyl)acetamide (CAS 332947-87-2)
- 3-Phenyl-1-(4-phenyl-2-thiazolyl)-4-[(4-chloro-3-nitrophenyl)hydrazone]-1H-pyrazole-4,5-dione (CAS 332420-90-3)
- 2-((5-(4-Chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 443740-19-0)
- 2-(2-(2,6-Difluorophenoxy)ethyl)-1,3-dioxolane (CAS 1443345-72-9)
- Ethyl 4-((2-chlorobenzoyl)oxy)-3-methylbenzofuran-2-carboxylate (CAS 356586-77-1)
- 7-methylquinazolin-6-amine (CAS 2403843-27-4)
- 5-[(4-ethylphenyl)amino]-1,3,4-thiadiazole-2-thiol (CAS 565198-66-5)
- 3-(4-Chlorophenoxy)aniline (CAS 105945-24-2)
- Varenicline Impurity 62 (CAS CATO-C4X-196262)
- N-(4-aminophenyl)-3-iodobenzamide hydrochloride (CAS 1583110-05-7)
- Isopropyl 2,4-dichloropyrimidine-5-carboxylate (CAS 69312-43-2)
- (4-Bromo-2-fluorobenzyl)(4-fluorophenyl)sulfane (CAS 1275698-27-5)
- Dulaglutide (CAS 923950-08-7)
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