N-[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]-2-methyl-propanamide CAS 444289-27-4
| CAS No. | 444289-27-4 |
| Molecular Formula | C17H17N3O5 |
| Molecular Weight | 343.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of N-[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]-2-methyl-propanamide (C17H17N3O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies N-[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]-2-methyl-propanamide (CAS 444289-27-4), a certified reference material (molecular formula C17H17N3O5, MW 343.33 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]-2-methyl-propanamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H17N3O5 |
| Molecular Weight | 343.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
Related N Standards
- 2-((9,10-Dioxo-9,10-dihydroanthracen-1-yl)amino)benzoic acid (CAS 19795-96-1)
- 4-[[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]amino]butanal (CAS 2415653-32-4)
- N-[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]butanamide (CAS 444288-09-9)
- 2-(2,6-dioxo-3-piperidyl)-5-(pentylamino)isoindoline-1,3-dione (CAS 1809556-66-8)
- 2-(2,6-dioxo-3-piperidyl)-1-oxo-N-sec-butyl-isoindoline-5-carboxamide (CAS 2390706-14-4)
- 2-(2,6-dioxo-3-piperidyl)-4-(pentylamino)isoindoline-1,3-dione (CAS 444287-97-2)
- 2-(2,6-dioxo-3-piperidyl)-N-isobutyl-1-oxo-isoindoline-4-carboxamide (CAS 2404339-89-3)
- N-[[2-(2,6-dioxo-3-piperidyl)-3-oxo-isoindolin-5-yl]methyl]butanamide (CAS 2761406-53-3)
Recommended Standards
- N-(benzo[d][1,3]dioxol-5-yl)-4-(furan-2-carbonyl)piperazine-1-carboxamide (CAS 708242-45-9)
- N-(5-(4-Fluorophenyl)-1,3,4-thiadiazol-2-yl)benzo[d][1,3]dioxole-5-carboxamide (CAS 476463-32-8)
- N-Allyl-2-((1-(2-(trifluoromethyl)phenyl)-1H-tetrazol-5-yl)thio)acetamide (CAS 941876-73-9)
- N-(4-Fluorophenyl)-2-(4-nitrophenyl)-1,3-thiazole-4-carboxamide (CAS 400080-64-0)
- pyrazolo[1,5-b]pyridazin-6-ol (CAS 2411637-09-5)
- 3-Methyl-1-(triphenylphosphoranylidene)butan-2-one (CAS 19753-67-4)
- (R)-2-(2-chlorobenzylamino)-1-(2,3-dihydro-1H-inden-1-yl)-1H-imidazo[4,5-b]pyridine-5-carboxamide 1202159-38-3 QC-11650 (CAS 1202159-38-3)
- DOTA(OtBu)3 (CAS 137076-54-1)
- 2-(methylamino)pyridine-3-carbaldehyde (CAS 32399-08-9)
- 2-((3-Bromobenzyl)thio)-3-(4-chlorophenyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one (CAS 618432-12-5)
- 1-Cyclohexyl-1,2,3,4-tetrahydroisoquinoline (CAS 87443-64-9)
- tert-Butyl 3-(4-chlorophenyl)-3-hydroxypiperidine-1-carboxylate (CAS 951624-09-2)
- 1-Methyl-N-(pyridin-3-ylmethyl)-1h-pyrazol-3-amine (CAS 1006952-69-7)
- (His32,Leu34)-Neuropeptide Y (32-36) (CAS 168916-68-5)
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