5-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)-4,5-dihydroisoxazole-3-carboxylic acid CAS 444342-51-2
| CAS No. | 444342-51-2 |
| Molecular Formula | C7H5F6NO4 |
| Molecular Weight | 281.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, 5-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)-4,5-dihydroisoxazole-3-carboxylic acid is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 281.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 5-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)-4,5-dihydroisoxazole-3-carboxylic acid (CAS 444342-51-2), a certified reference material (molecular formula C7H5F6NO4, MW 281.11 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)-4,5-dihydroisoxazole-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5F6NO4 |
| Molecular Weight | 281.11 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Hexafluoro Standards
- [(Z)-(1,1,1,5,5,5-Hexafluoro-4-oxopentan-2-ylidene)amino]thiourea (CAS 691879-66-0)
- (E)-1,1,1,5,5,5-hexafluoro-4-((trimethylsilyl)oxy)pent-3-en-2-one (CAS 75108-34-8)
- 4,5,5,6,6,6-Hexafluoro-4-(trifluoromethyl)hexan-1-ol (CAS 239463-96-8)
- 1,1,1,3,3,3-Hexafluoro-2-iodopropane (CAS 4141-91-7)
- 2',3,3',4',5',6'-Hexafluoro[1,1'-biphenyl]-4-amine (CAS 893737-79-6)
- 1,1,1,2,3,3-hexafluoro-3-(trichloromethoxy)propane 1,1,1,2,3,3-hexakis(fluoranyl)-3-(trichloromethyloxy)propane 56860-83-4 A831213 (CAS 56860-83-4)
- 2,2,3,3,4,4-Hexafluoro-4-sulfobutanoic acid (CAS 83071-25-4)
- (Z)-4,5,5,6,6,6-hexafluoro-4-(trifluoromethyl)hex-2-en-1-ol (CAS 239463-99-1)
Recommended Standards
- 4-Bromo-7-methoxyquinoline-6-carboxamide (CAS 2089310-92-7)
- 5-(4-Bromophenyl)-1H-pyrazole-3-carbohydrazide (CAS 306749-73-5)
- 4-Bromo-5-methyl-1-phenylpyrazole-3-carboxylic acid (CAS 73227-92-6)
- 5-(4-Bromophenyl)-1-methyl-1H-pyrazole-3-carboxylic Acid (CAS 852815-32-8)
- 1-(4,6-Diamino-1,3,5-triazin-2-yl)-2-methylpropan-1-one (CAS 30099-83-3)
- 2-Amino-N-(1,1-dioxidothietan-3-yl)pent-4-ynamide (CAS 1849767-58-3)
- (R)-1-(3,4-dimethoxyphenyl)but-3-en-1-amine (CAS 1270175-06-8)
- Fluticasone Impurity 105 (CAS CATO-C4X-1650105)
- 3-Methyl-2-oxo-2,3-dihydro-1H-pyrido[3,4-b][1,4]oxazine-7-carbonitrile (CAS 1956369-57-5)
- 2,3,4-Trifluorobenzonitrile (CAS 143879-80-5)
- 2-(3-Aminothietan-3-yl)ethanol (CAS 1545881-41-1)
- 4-(4-Fluorophenoxy)-5-methoxy-2-phenylpyrimidine (CAS 860788-29-0)
- Neosaxitoxin (CAS 64296-20-4)
- [His]1-Acetylated Semaglutide (CAS CATO-C4X-2226219)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com