8-Bromo-1,2,3,4-tetrahydronaphthalen-2-ol CAS 444619-84-5

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 8-Bromo-1,2,3,4-tetrahydronaphthalen-2-ol.

8-Bromo-1,2,3,4-tetrahydronaphthalen-2-ol (CAS 444619-84-5), molecular formula C10H11BrO and molecular weight 227.10 g/mol, is a CATO reference standard with documented purity and traceability.

Based on its molecular formula C10H11BrO, 8-Bromo-1,2,3,4-tetrahydronaphthalen-2-ol contains a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 227.10 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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