8-fluoro-2H-isoquinolin-1-one CAS 444898-84-4
| CAS No. | 444898-84-4 |
| Molecular Formula | C9H6FNO |
| Molecular Weight | 163.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 8-fluoro-2H-isoquinolin-1-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
8-fluoro-2H-isoquinolin-1-one (CAS 444898-84-4), molecular formula C9H6FNO and molecular weight 163.15 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 8-fluoro-2H-isoquinolin-1-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 163.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 8-fluoro-2H-isoquinolin-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H6FNO |
| Molecular Weight | 163.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related fluoro Standards
- 3-fluoro-1,2-dihydroquinolin-2-one (CAS 124467-22-7)
- 2-Fluoro-6-(1h-imidazol-1-yl)pyridine (CAS 1250924-92-5)
- 5-Fluoro-2-(1H-pyrazol-1-yl)pyridine (CAS 1259030-32-4)
- 4-Fluoro-2-hydroxyquinoline (CAS 1261539-01-8)
- 4-Fluoro-5-hydroxyquinoline (CAS 1261625-23-3)
- 4-Fluoro-6-hydroxyquinoline (CAS 1261678-34-5)
- 5-Fluoro-2-(1H-imidazol-1-yl)pyridine (CAS 1287217-29-1)
- 7-Fluoro-1H-indole-2-carbaldehyde (CAS 1367930-66-2)
Recommended Standards
- 7-Fluoroquinoxalin-6-amine (CAS 920034-10-2)
- 8-Fluoro-4-hydroxyquinoline (CAS 63010-71-9)
- 7-Fluoroquinolin-4-ol (CAS 391-83-3)
- 8-Fluoroisoquinolin-3(2H)-one (CAS 51463-16-2)
- 2-Benzyl-2,7-diazaspiro[3.5]nonane hydrochloride (CAS 2177265-01-7)
- 3-Indoleacetamide (CAS 879-37-8)
- (R)-1-(2-Oxo-1-(2-oxo-2-(o-tolyl)ethyl)-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-3-(m-tolyl)urea (CAS 145084-28-2)
- 4-Chloro-6-phenyl-5H-pyrrolo[3,2-d]pyrimidine (CAS 875340-50-4)
- 1-Benzyl-3-(3-(dimethylamino)propoxy)-N-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide (CAS 268725-86-6)
- (r)-1-(1-Amino-2-hydroxyethyl)naphthalen-2-ol (CAS 1213094-34-8)
- 3-Methyl-3H-pyrazolo[3,4-b]pyridine (CAS 877773-22-3)
- 1-BRomo-2-methylcyclohex-1-ene (CAS 99747-75-8)
- ({[1,1'-Biphenyl]-4-yl}methyl)(propyl)amine (CAS 893574-35-1)
- Peptide T (CAS 106362-32-7)
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