Cyclopamine CAS 4449-51-8

Purity >95%In StockPharmaceutical Standards
CAS No.4449-51-8
Molecular FormulaC27H41NO2
Molecular Weight411.62 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Cyclopamine CAS 4449-51-8 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 411.62 g/mol gives Cyclopamine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Cyclopamine (CAS 4449-51-8) is a high-purity analytical reference standard with the molecular formula C27H41NO2 and a molecular weight of 411.62 g/mol.

Structurally, Cyclopamine (C27H41NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 411.62 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures Cyclopamine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC27H41NO2
Molecular Weight411.62 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>95%
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1958
Nitrogen Atoms1

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