(2,2,3,3-Tetrafluoro-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methanol CAS 444919-46-4
| CAS No. | 444919-46-4 |
| Molecular Formula | C9H6F4O3 |
| Molecular Weight | 238.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (2,2,3,3-Tetrafluoro-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methanol is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(2,2,3,3-Tetrafluoro-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methanol (CAS 444919-46-4) is a high-purity analytical reference standard with the molecular formula C9H6F4O3 and a molecular weight of 238.14 g/mol.
Structurally, (2,2,3,3-Tetrafluoro-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methanol (C9H6F4O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 238.14 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (2,2,3,3-Tetrafluoro-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H6F4O3 |
| Molecular Weight | 238.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Tetrafluoro Standards
- 2,2,3,3-Tetrafluoro-2,3-dihydrobenzo[b][1,4]dioxine-6,7-diamine (CAS 110968-70-2)
- 2,3,4,5-Tetrafluoro-6-nitrobenzoic acid (CAS 16583-08-7)
- 1,2,3,4-Tetrafluoro-5,6-dinitrobenzene (CAS 16582-87-9)
- (E)-4,5,5,5-tetrafluoro-4-(trifluoromethyl)pent-2-enoic Acid (CAS 243139-64-2)
- Ethyl 2,3,5,6-tetrafluoro-4-methylbenzoate (CAS 1076197-35-7)
- 2,3,5,6-Tetrafluoro-4-(trifluoromethyl)phenol 2,3,5,6-Tetrafluoro-4-hydroxybenzotrifluoride 2787-79-3 Perfluoro-p-cresol T1983 alpha,alpha,alpha,2,3,5,6-Heptafluoro-p-cresol (CAS 2787-79-3)
- 2,2,3,3-Tetrafluoro-1,4-benzodioxane-5- carboxaldehyde (CAS 119922-99-5)
- 2,2,3,3-Tetrafluoro-2,3-dihydrobenzo[b][1,4]dioxine-6-carbaldehyde (CAS 159276-63-8)
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