tert-Butyl 4-bromo-2-methylbenzoate CAS 445003-37-2
| CAS No. | 445003-37-2 |
| Molecular Formula | C12H15BrO2 |
| Molecular Weight | 271.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
tert-Butyl 4-bromo-2-methylbenzoate (C12H15BrO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
tert-Butyl 4-bromo-2-methylbenzoate (CAS 445003-37-2) is a high-purity analytical reference standard with the molecular formula C12H15BrO2 and a molecular weight of 271.15 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures tert-Butyl 4-bromo-2-methylbenzoate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H15BrO2 |
| Molecular Weight | 271.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
Recommended Standards
- tert-Butyl 2-bromo-2-phenylacetate (CAS 35132-16-2)
- tert-Butyl 4-bromo-3-methylbenzoate (CAS 347174-28-1)
- tert-Butyl 2-(4-Bromophenyl)acetate (CAS 33155-58-7)
- UF010, 98% (CAS 537672-41-6)
- N-(2-(Methylthio)benzo[d]thiazol-6-yl)benzo[d]thiazole-6-carboxamide (CAS 681167-06-6)
- 2-(((3-Methyl-1,2,4-oxadiazol-5-yl)methyl)thio)acetic acid (CAS 1042797-51-2)
- 4-Methyl-2-(2-oxo-4-(2-(trifluoromethoxy)phenoxy)pyridin-1(2H)-yl)pentanoic acid (CAS 1262239-28-0)
- 2-Methoxymorpholine-4-carbaldehyde (CAS 90862-41-2)
- 2-{[bis(4-fluorophenyl)methoxy]methyl}oxirane (CAS 99580-00-4)
- 2-bromo-1,1-dimethoxycyclobutane (CAS 20121-72-6)
- 5-[(5-bromo-2-methoxyphenyl)methyl]-1h-1,2,3,4-tetrazole (CAS 1247522-13-9)
- tert-butyl 2-(2-bromoethoxy)benzoate (CAS 1803582-73-1)
- tert-butyl 2-[(2-phenylethyl)amino]acetate (CAS 66937-52-8)
- Tirzepatide Impurity 46 (CAS CATO-C4X-324046)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com