3-Amino-N-(3,5-dichlorophenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide CAS 445267-47-0
| CAS No. | 445267-47-0 |
| Molecular Formula | C19H12Cl2N4OS |
| Molecular Weight | 415.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Amino-N-(3,5-dichlorophenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide.
3-Amino-N-(3,5-dichlorophenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide (CAS 445267-47-0) is a high-purity analytical reference standard with the molecular formula C19H12Cl2N4OS and a molecular weight of 415.30 g/mol.
The molecular framework of 3-Amino-N-(3,5-dichlorophenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide (C19H12Cl2N4OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Amino-N-(3,5-dichlorophenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H12Cl2N4OS |
| Molecular Weight | 415.30 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 3-Amino-N-(2,5-dichlorophenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide (CAS 445267-30-1)
- 3-Amino-N-(2,6-dichlorophenyl)-6-(pyridin-3-yl)thieno[2,3-b]pyridine-2-carboxamide (CAS 625370-72-1)
- 2-Amino-9-((2R,3R,4R,5R)-3-(((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-6H-purin-6-one (CAS 148711-49-3)
- (3-Amino-6-methyl-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl)(4-bromophenyl)methanone (CAS 299198-16-6)
- 5-Amino-4-hydroxynaphthalene-1,6-disulfonic acid (CAS 6271-89-2)
- 1-Amino-2,4-dibromo-7-chloroanthracene-9,10-dione (CAS 88605-95-2)
- 4-Amino-2,5-dichlorobenzene-1-sulfonyl fluoride (CAS 5312-75-4)
- 3-Amino-2-(1-hydroxyheptadecyl)quinazolin-4(3H)-one (CAS 917764-64-8)
Recommended Standards
- Bis(isocyanocyclohexane)gold(1+) (CAS 49866-97-9)
- (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(5-nitro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate (CAS 194474-73-2)
- {2-[(4-bromophenyl)sulfanyl]pyridin-3-yl}methyl N-phenylcarbamate (CAS 478031-10-6)
- 4-(tert-Butyl)-N'-((5-(3,4-dichlorophenyl)furan-2-yl)methylene)benzohydrazide (CAS 328922-22-1)
- methyl 1-methyl-1H-imidazole-2-carboxylate (CAS 62366-53-4)
- 2,3,3',4,4',5-Hexabromodiphenyl ether (CAS 405237-85-6)
- 2,5-Dibromoterephthalaldehyde (CAS 63525-48-4)
- 6-Amino-2-chloro-3-methoxyphenol hydrochloride (CAS 1956322-80-7)
- 1-(Bromomethyl)pyrrolidin-2-one (CAS 93287-12-8)
- 3-((2,4-Dichlorobenzyl)thio)-N-(4-(trifluoromethoxy)phenyl)thiophene-2-carboxamide (CAS 251097-50-4)
- (1S,2R)-2-(((Benzyloxy)carbonyl)amino)cyclobutane-1-carboxylic acid (CAS 517913-99-4)
- Ethyl 5-chloro-1-(4-chlorophenyl)-1H-1,2,3-triazole-4-carboxylate (CAS 30165-93-6)
- 3,4-Diamino-N-(4-chlorophenyl)benzenesulfonamide (CAS 380342-96-1)
- FMRF Amide Related Peptide. (CAS 149471-12-5)
Why CATO?
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