3-Amino-N-(5-fluoro-2-methylphenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide CAS 445267-49-2
| CAS No. | 445267-49-2 |
| Molecular Formula | C20H15FN4OS |
| Molecular Weight | 378.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-Amino-N-(5-fluoro-2-methylphenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3-Amino-N-(5-fluoro-2-methylphenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide (CAS 445267-49-2), molecular formula C20H15FN4OS and molecular weight 378.42 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Amino-N-(5-fluoro-2-methylphenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide (C20H15FN4OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H15FN4OS |
| Molecular Weight | 378.42 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 1-Amino-2-methyl-4-(naphthalen-2-ylamino)anthracene-9,10-dione (CAS 74165-76-7)
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Recommended Standards
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- 3,3'-((9,10-Dioxo-9,10-dihydroanthracene-1,4-diyl)bis(azanediyl))dibutanal (CAS 89734-95-2)
- 2-((2,2,2-Trifluoroethyl)sulfonyl)benzo[d]thiazole (CAS 1465812-79-6)
- 6,7-Dimethoxy-1-(3-methylbut-1-en-1-yl)-3,4-dihydroisoquinoline (CAS 61170-45-4)
- 4-Bromo-7-methoxy-2,2-dimethyl-2,3-dihydrobenzofuran (CAS 185406-76-2)
- Ethyl 1-phenyl-5-(phenylamino)-1H-imidazole-4-carboxylate (CAS 68695-58-9)
- (4-(Azetidin-1-ylmethyl)phenyl)methanamine (CAS 926225-09-4)
- (3-methanesulfonylphenyl)methanesulfonyl chloride (CAS 1368630-29-8)
- 2-(2-Bromo-5-fluorophenyl)propan-2-ol (CAS 853271-16-6)
- 2-phenylpiperazine dihydrochloride (CAS 872139-22-5)
- 2-(1-(4-Nitrobenzyl)-2-oxo-1,2-dihydroquinolin-4-yl)acetonitrile (CAS 61304-97-0)
- Boc-Cholecystokinin Octapeptide (desulfated) (A-1295.0001) (CAS 25687-34-7)
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