3-Amino-N-(5-((2-chlorobenzyl)thio)-1,3,4-thiadiazol-2(3H)-ylidene)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide CAS 445267-60-7
| CAS No. | 445267-60-7 |
| Molecular Formula | C22H15ClN6OS3 |
| Molecular Weight | 511.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
3-Amino-N-(5-((2-chlorobenzyl)thio)-1,3,4-thiadiazol-2(3H)-ylidene)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide (CAS 445267-60-7) is a high-purity analytical reference standard with the molecular formula C22H15ClN6OS3 and a molecular weight of 511.04 g/mol.
Structurally, 3-Amino-N-(5-((2-chlorobenzyl)thio)-1,3,4-thiadiazol-2(3H)-ylidene)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide (C22H15ClN6OS3) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 18.0, corresponding to approximately 18 ring(s) or double-bond equivalent(s). With a molecular weight of 511.04 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C22H15ClN6OS3 |
| Molecular Weight | 511.04 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 3 |
Related Amino Standards
- 3-Amino-N-(5-{[(4-chlorophenyl)methyl]sulfanyl}-1,3,4-thiadiazol-2-yl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide (CAS 445267-61-8)
- (S)-4-(4-(2-Amino-2-hydroxypropyl)-2,6-diiodophenoxy)phenol (CAS 1380782-27-3)
- 3-Amino-4-(benzo[d][1,3]dioxol-5-yl)-N-(4-nitrophenyl)-6-phenylthieno[2,3-b]pyridine-2-carboxamide (CAS 332053-71-1)
- 3-Amino-N,4,6-tris(4-methoxyphenyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 332156-07-7)
- N-(6-Amino-2,4-dioxo-1,3-dipropyl-1,2,3,4-tetrahydropyrimidin-5-yl)-3,5-dichloro-2-(2,2,2-trifluoroacetamido)benzamide (CAS 154623-75-3)
- 2-Amino-6-chloro-9-(2-deoxy-3,5-di-O-benzoyl-2-fluoro-β-D-arabinofuranosyl)purine (CAS 118373-61-8)
- 6-Amino-2-chloro-9-(2'-deoxy-2-fluoro-3',5'-di-O-benzoyl-β-D-arabinofuranosyl)-9H-purine (CAS 355138-50-0)
- 3-Amino-4-(3,4-dimethoxyphenyl)-N-(2,4-dimethylphenyl)-6-phenylthieno[2,3-b]pyridine-2-carboxamide (CAS 332040-54-7)
Recommended Standards
- N-(5-chloro-2-methoxyphenyl)-2-((5-((4-methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 332912-73-9)
- Fluocinolone Acetonide Impurity 15 (CAS 1181-32-4)
- N-([1,1'-Biphenyl]-2-yl)-2-((5-(4-chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 332947-88-3)
- Eldecalcitol Impurity 37 (CAS 235107-98-9)
- 7-(Bromomethyl)-4H-chromen-4-one (CAS 331683-65-9)
- 5-BRomo-4-chloro-3-indolyl phenyl phosphate, p-toluidine salt (CAS 1171461-61-2)
- (R)-3-(Benzo[d][1,3]dioxol-5-yl)-2-(((tert-butoxycarbonyl)amino)methyl)propanoic acid (CAS 1260606-71-0)
- N-(Pyrimidin-2-yl)-1-oxa-7-azaspiro[4.4]nonan-3-amine (CAS 1422060-29-4)
- (1R,3S)-3-((Benzyloxy)carbonyl)-2,2-dimethylcyclobutane-1-carboxylic acid (CAS 1616705-62-4)
- 5-Methyl-1-phenylhexan-3-one (CAS 78987-82-3)
- 4'-(Furan-2-yl)-2,2':6',2''-terpyridine (CAS 375382-77-7)
- (S)-tert-Butyl 2-formyl-5-oxopyrrolidine-1-carboxylate (CAS 185303-87-1)
- Ethyl 2-pyrrolidin-3-ylacetate (CAS 756818-49-2)
- (Pro3)-Gastric Inhibitory Polypeptide (human) trifluoroacetate salt (CAS 299898-52-5)
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