(3-Amino-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl)(3,4-dimethoxyphenyl)methanone CAS 445269-20-5
| CAS No. | 445269-20-5 |
| Molecular Formula | C22H24N2O3S |
| Molecular Weight | 396.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 396.50 g/mol gives (3-Amino-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl)(3,4-dimethoxyphenyl)methanone distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(3-Amino-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl)(3,4-dimethoxyphenyl)methanone (CAS 445269-20-5), molecular formula C22H24N2O3S and molecular weight 396.50 g/mol, is a CATO reference standard with documented purity and traceability.
(3-Amino-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl)(3,4-dimethoxyphenyl)methanone (C22H24N2O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (3-Amino-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl)(3,4-dimethoxyphenyl)methanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H24N2O3S |
| Molecular Weight | 396.50 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 3-Amino-6-isopropyl-N-(4-methoxyphenyl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide (CAS 728000-33-7)
- 4-Amino-5-benzoyl-2-{[2-(4-fluorophenyl)-2-oxoethyl]sulfanyl}thiophene-3-carbonitrile (CAS 478081-63-9)
- 2-(2-Amino-1H-benzo[d]imidazol-1-yl)-N-benzyl-8-methoxyquinazolin-4-amine (CAS 1346527-98-7)
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- 6-Amino-1-benzyl-5-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 554405-18-4)
- 6-Amino-1H-pyrrolo[3,2-c]pyridin-4-ol (CAS 75938-36-2)
- benzyl 2-((2-amino-3-carbamoylphenyl)carbamoyl)-2-methylpyrrolidine-1-carboxylate (CAS 912444-71-4)
- 6-Amino-2-(2,4-dimethylphenyl)-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinoline-5-sulfonic acid (CAS 93942-76-8)
Recommended Standards
- (1-Tosylpiperidine-4-carbonyl)-L-alloisoleucine (CAS 956923-60-7)
- (E)-1-[4-(2,4-Dimethylphenyl)piperazino]-3-[4-(3-fluoropropoxy)phenyl]-2-propen-1-one (CAS 477871-20-8)
- Z-Leu-Met-OH (C-2155.0025) (CAS 18830-16-5)
- (S)-3-(Hexadecyloxy)-2-hydroxypropyl dihydrogen phosphate (CAS 52603-03-9)
- 2-((1,1-Dioxidobenzo[d]isothiazol-3(2H)-ylidene)amino)benzoic acid (CAS 108950-06-7)
- Disperse blue 106 press cake (CAS 104573-53-7)
- H-Tic(OH)-OH . 2H (CAS 210709-23-2)
- 2-(Diethylphosphoryl)acetonitrile (CAS 13298-29-8)
- 2,2'-Dimethyl-[1,1'-biphenyl]-4,4'-dicarbaldehyde (CAS 100207-94-1)
- 2-Fluoro-1-isopropoxy-3-methoxybenzene (CAS 1369918-05-7)
- 4-(2-Bromoethyl)-2,2-dimethyl-1,3-dioxolane (CAS 89942-18-7)
- (3r,4s)-1-(Tert-butoxycarbonyl)-4-(2-hydroxyphenyl)pyrrolidine-3-carboxylic acid (CAS 1392212-25-7)
- 2-Cyclohexylpiperidin-3-ol (CAS 1369238-92-5)
- D-Ile27-Tirzepatide (CAS CATO-CPTD788907)
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