(3-Amino-6-methyl-4-(thiophen-2-yl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridin-2-yl)(4-methoxyphenyl)methanone CAS 445384-48-5
| CAS No. | 445384-48-5 |
| Molecular Formula | C23H21N3O2S2 |
| Molecular Weight | 435.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, (3-Amino-6-methyl-4-(thiophen-2-yl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridin-2-yl)(4-methoxyphenyl)methanone is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 435.56 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
(3-Amino-6-methyl-4-(thiophen-2-yl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridin-2-yl)(4-methoxyphenyl)methanone (CAS 445384-48-5) is a high-purity analytical reference standard with the molecular formula C23H21N3O2S2 and a molecular weight of 435.56 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H21N3O2S2 |
| Molecular Weight | 435.56 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related Amino Standards
- (3-Amino-6-methyl-4-(thiophen-2-yl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridin-2-yl)(3-methoxyphenyl)methanone (CAS 496804-98-9)
- (S)-2-Amino-3-(5-(bis(2-chloroethyl)amino)-1-(p-tolyl)-1H-benzo[d]imidazol-2-yl)propanoic acid (CAS 72437-91-3)
- (R)-2-Amino-3-((3,5-dichloro-6-((diethoxyphosphorothioyl)oxy)pyridin-2-yl)thio)propanoic acid (CAS 870971-31-6)
- 2-Amino-5-(3-((4-(4-(2-(chloromethyl)-1,3-dioxolan-2-yl)butyl)phenyl)amino)propyl)-6-methylpyrimidin-4(3H)-one (CAS 2499-42-5)
- 4-Amino-7-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)pyrido[2,3-d]pyrimidine-6-carbonitrile (CAS 338410-29-0)
- 2-((6-Amino-3-methyl-2,4-dioxo-1-phenyl-1,2,3,4-tetrahydropyrimidin-5-yl)carbamoyl)-6-isopropylphenyl acetate (CAS 301206-06-4)
- 3-Amino-6-(pyridin-4-yl)-N-(3,4,5-trimethoxyphenyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 445267-51-6)
- 2-Amino-4-(1,3-diphenyl-1H-pyrazol-4-yl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (CAS 303794-12-9)
Recommended Standards
- 4,4'-(9-Hexyl-9H-carbazole-2,7-diyl)diphenol (CAS 2757730-56-4)
- (E)-4-(4-(1,2,2-Triphenylvinyl)styryl)pyridine (CAS 1421768-47-9)
- Methyl 3-[2-({2-[2-(diethylamino)acetamido]phenyl}sulfanyl)acetamido]thiophene-2-carboxylate (CAS 478045-06-6)
- 2-({3-methyl-4-oxo-7-phenyl-3H,4H-thieno[3,2-d]pyrimidin-2-yl}sulfanyl)-N-[(4-methylphenyl)methyl]acetamide (CAS 1111418-13-3)
- 4-Nitrosoresorcinol (CAS 698-31-7)
- 2-(6-Methylpyridin-2-yl)-1-oxo-1,2-dihydroisoquinoline-4-carboxylic acid (CAS 1429903-58-1)
- 3-(Prop-2-yn-1-yl)pyrrolidine-3-carboxylic acid (CAS 1509635-31-7)
- 3-Hydroxy-5-pentylcyclohex-2-en-1-one (CAS 58016-29-8)
- 3-Chloro-4-methyl-1H-pyrrolo[2,3-b]pyridin-5-ol (CAS 1190313-06-4)
- 2-(Chloromethyl)-3-(difluoromethyl)-6-iodopyridine-4-acetic acid (CAS 1805611-60-2)
- 1-(3-Hydroxycyclobutyl)ethan-1-one (CAS 30494-01-0)
- 3-Methylbut-2-en-2-yl trifluoromethanesulfonate (CAS 28143-80-8)
- 4-Bromo-6-chloro-2,3-difluoroaniline (CAS 1895912-80-7)
- Semaglutide impurity 57 (CAS 2773558-06-6)
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