Propan-2-yl 2-{[3-cyano-6-methyl-4-(thiophen-2-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl]sulfanyl}acetate CAS 445384-91-8
| CAS No. | 445384-91-8 |
| Molecular Formula | C19H21N3O2S2 |
| Molecular Weight | 387.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Propan-2-yl 2-{[3-cyano-6-methyl-4-(thiophen-2-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl]sulfanyl}acetate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Propan-2-yl 2-{[3-cyano-6-methyl-4-(thiophen-2-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl]sulfanyl}acetate (CAS 445384-91-8) is a high-purity analytical reference standard with the molecular formula C19H21N3O2S2 and a molecular weight of 387.52 g/mol.
The molecular framework of Propan-2-yl 2-{[3-cyano-6-methyl-4-(thiophen-2-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl]sulfanyl}acetate (C19H21N3O2S2) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H21N3O2S2 |
| Molecular Weight | 387.52 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
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Recommended Standards
- N-(4-(Dimethylamino)phenyl)-2-((4-ethyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 618412-18-3)
- Mianserin impurity 24 (CAS CATO-C4X-136924)
- N-(2-Aminoethyl)-N-(2-(phenylthio)ethyl)isoquinoline-5-sulfonamide (CAS 651307-21-0)
- Mianserin Impurity 83 (CAS CATO-C4X-136983)
- 1-(Propane-2-sulfonyl)pyrrolidin-3-one (CAS 1934691-33-4)
- 5-(Chloromethyl)-3-fluoro-2-methoxypyridine (CAS 1211535-18-0)
- tert-Butyl [(1-picolinoylpiperidin-4-yl)methyl]carbamate (CAS 1349716-50-2)
- Xylometazoline EP Impurity B (CAS 19387-83-8)
- Tert-butyl 3-(dimethylamino)pyrrolidine-1-carboxylate (CAS 1246434-09-2)
- (R)-1-(2,4-difluorophenyl)-2-methoxyethan-1-amine (CAS 1270276-12-4)
- 8-Bromo-5H-[1,2,4]triazino[5,6-b]indol-3-amine (CAS 910443-21-9)
- 4-(N-Methyl-N-nitrosamino)-4-(3-pyridyl)butane-1-ol (CAS 59578-66-4)
- 5,6,7,8-Tetrahydroimidazo[1,5-a]pyridine-1-carboxylic acid (CAS 1520287-70-0)
- Semaglutide impurity 255 (CAS CATO-C4X-2226255)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com