(5,6,7,8-Tetrahydro-[1,8]naphthyridin-2-yl)-acetic acid CAS 445490-61-9
| CAS No. | 445490-61-9 |
| Molecular Formula | C10H12N2O2 |
| Molecular Weight | 192.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(5,6,7,8-Tetrahydro-[1,8]naphthyridin-2-yl)-acetic acid (CAS 445490-61-9), molecular formula C10H12N2O2 and molecular weight 192.21 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, (5,6,7,8-Tetrahydro-[1,8]naphthyridin-2-yl)-acetic acid (C10H12N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 192.21 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H12N2O2 |
| Molecular Weight | 192.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
Related Tetrahydro Standards
- Methyl 5,6,7,8-tetrahydro-1,6-naphthyridine-2-carboxylate (CAS 1057855-79-4)
- Methyl 5,6,7,8-tetrahydro-1,6-naphthyridine-3-carboxylate (CAS 1086392-58-6)
- 7-Methyl-1,2,3,4-tetrahydro-[1,8]naphthyridine-2-carboxylic acid (CAS 1246548-23-1)
- Methyl 5,6,7,8-tetrahydro-1,7-naphthyridine-3-carboxylate (CAS 1253888-80-0)
- 2,3,4,5-tetrahydro-1,6-benzodioxocine-8-carbaldehyde (CAS 170708-98-2)
- Methyl 5,6,7,8-tetrahydro-1,5-naphthyridine-3-carboxylate (CAS 1823947-71-2)
- Methyl 5,6,7,8-tetrahydro-1,5-naphthyridine-2-carboxylate (CAS 1824049-93-5)
- Methyl 1,2,3,4-tetrahydro-1,6-naphthyridine-2-carboxylate (CAS 875515-01-8)
Recommended Standards
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- (4-Methoxy-3-(prop-2-yn-1-yloxy)phenyl)methanol (CAS 385383-49-3)
- (5S,6R)-Methyl 5,6,7-trihydroxyheptanoate (CAS 78606-80-1)
- 4-Methylthiophene-3-carbonitrile (CAS 73229-39-7)
- 1-((3-Aminoquinolin-4-yl)amino)-2-methylpropan-2-ol (CAS 129655-59-0)
- Methyl (S)-3-amino-3-(pyridin-3-yl)propanoate hydrochloride (CAS 1217624-51-5)
- 2,5-Dimethyl-1-(1,3-thiazol-2-yl)-1h-pyrrole-3-carboxylic acid (CAS 953902-12-0)
- N-Cyclohexyl-N-ethyl-2-(methylamino)acetamidehydrochloride (CAS 1219972-30-1)
- 4-Hydroxy-3,6-dimethyl-1,2-dihydropyridin-2-one (CAS 4664-13-5)
- Momelotinib impurity 2 (CAS CATO-C4X-33772)
- 6-(1h-Imidazol-1-yl)-2-methyl-2-(methylamino)hexanamide (CAS 1248216-43-4)
- Cephalexin Dimer (CAS CATO-C4X-126111)
- Liraglutide(14-22)TFA Salt (CAS CATO-C4X-199212)
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