2-(5-Fluoro-2-methoxyphenyl)quinoline-4-carboxylic acid CAS 446-77-5
| CAS No. | 446-77-5 |
| Molecular Formula | C17H12FNO3 |
| Molecular Weight | 297.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 297.28 g/mol gives 2-(5-Fluoro-2-methoxyphenyl)quinoline-4-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(5-Fluoro-2-methoxyphenyl)quinoline-4-carboxylic acid (CAS 446-77-5) is a high-purity analytical reference standard with the molecular formula C17H12FNO3 and a molecular weight of 297.28 g/mol.
The molecular framework of 2-(5-Fluoro-2-methoxyphenyl)quinoline-4-carboxylic acid (C17H12FNO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(5-Fluoro-2-methoxyphenyl)quinoline-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H12FNO3 |
| Molecular Weight | 297.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
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- Methyl 3-(2-fluoro-4-nitrophenoxy)thiophene-2-carboxylate (CAS 252026-46-3)
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Recommended Standards
- 2-(2H-1,3-Benzodioxol-5-yl)-4-(4-fluorophenyl)-4-oxobutanenitrile (CAS 329701-01-1)
- 2-(((4-Methoxyphenyl)sulfonyl)methyl)-5-nitrofuran (CAS 61266-76-0)
- 3-(4-Fluorophenyl)-N-methyl-4-oxo-3,4-dihydrophthalazine-1-carboxamide (CAS 339021-32-8)
- 1-(2-Fluorobenzyl)-3-formyl-1H-indole-2-carboxylic acid (CAS 903159-98-8)
- 8-Ethylchroman-4-amine (CAS 767610-47-9)
- 3,4-Difluoro-2-nitroaniline (CAS 292145-76-7)
- 1-Benzhydryl-3-methylazetidine (CAS 336182-51-5)
- 3-(((4-Bromobenzyl)sulfinyl)methyl)-5-((2,6-dichlorobenzyl)thio)-4-ethyl-4H-1,2,4-triazole (CAS 344275-04-3)
- 2-Amino-2-methylbutanenitrile hydrochloride (CAS 50846-37-2)
- 1-(Benzyloxy)-2-(2,4-dichlorophenyl)-1H-imidazo[4,5-b]pyridine (CAS 338978-60-2)
- n,n-Dimethyl-2-((thiophen-2-ylmethyl)amino)acetamide (CAS 1094673-25-2)
- (4-(TERT-BUTOXYCARBONYL)-3-FLUOROPHENYL-1,2,3,4,5,6-13C6)BORONIC ACID PINACOL ESTER (CAS 2304633-99-4)
- Thieno[3,2-b]furan, 5,6-bis(4-methoxyphenyl)-2,3-diphenyl- (CAS 81385-77-5)
- Semaglutide Impurity 163 (x TFA Salt) (CAS CATO-C4X-2226163)
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