1-[(4-Fluorophenyl)sulfonyl]-4-phenylpiperidine-4-carboxylic acid CAS 446029-84-1
| CAS No. | 446029-84-1 |
| Molecular Formula | C18H18FNO4S |
| Molecular Weight | 363.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-[(4-Fluorophenyl)sulfonyl]-4-phenylpiperidine-4-carboxylic acid (CAS 446029-84-1), molecular formula C18H18FNO4S and molecular weight 363.40 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C18H18FNO4S, 1-[(4-Fluorophenyl)sulfonyl]-4-phenylpiperidine-4-carboxylic acid contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 363.40 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H18FNO4S |
| Molecular Weight | 363.40 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Fluorophenyl Standards
- (Z)-[(4-Fluorophenyl)[2-(4-methylphenyl)cyclopropyl]methylidene]amino furan-2-carboxylate (CAS 338749-06-7)
- 2-[(3-Fluorophenyl)methyl]-6-phenyl-5-(piperidin-1-yl)-2,3-dihydropyridazin-3-one (CAS 861208-98-2)
- 1-[3-(4-Fluorophenyl)-2,1-benzisoxazol-5-yl]-1-ethanone N-(2-fluorophenyl)hydrazone (CAS 306978-26-7)
- 1-(2-fluorophenyl)-6-(4-methoxyphenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1011399-49-7)
- 2,4,6-tris(4-fluorophenyl)-1,3,5-triazine (CAS 130156-10-4)
- 2-(2-((6-(4-Fluorophenyl)pyridazin-3-yl)oxy)ethyl)isoindoline-1,3-dione (CAS 2097937-36-3)
- 2-(4-Fluorophenyl)-N-(4-(pyrrolidin-1-yl)butyl)quinolin-4-amine (CAS 510755-19-8)
- [1-[(4-Fluorophenyl)methyl]indol-3-yl]-(2,2,3,3-tetramethylcyclopropyl)methanone (CAS 2185863-15-2)
Recommended Standards
- 1-(2-(1H-indol-3-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)thiourea (CAS 404902-48-3)
- 2-[5-(4-Fluorobenzoyl)-2-thienyl]-3-(4-methoxyphenyl)acrylonitrile (CAS 338966-63-5)
- (3R,4S)-1-(tert-butoxycarbonyl)-4-(2-(ethoxycarbonyl)phenyl)pyrrolidine-3-carboxylic acid (CAS 873846-06-1)
- 4-Fluoro-N-(5-((4-fluorobenzyl)thio)-1,3,4-thiadiazol-2-yl)benzamide (CAS 607702-99-8)
- (2R,3S)-Methyl 2-methyl-3-(3-methylpyridin-2-yl)butanoate (CAS 2767008-09-1)
- 5-Bromo-6-hydroxynicotinaldehyde (CAS 952183-35-6)
- n-Dipropylamine-d4 Hydrochloride (CAS 1329834-71-0)
- 2-Pyridylacetic-α,α-d2 Acid-OD DCl (CAS 1219802-51-3)
- 4-Methoxy-1H-pyrrolo[3,2-c]pyridine-2-carboxylic acid (CAS 1242427-43-5)
- methyl 2-amino-4-methanesulfonylbenzoate (CAS 158580-87-1)
- 4-Methyl-3-(2-methylbenzenesulfonyl)-2-[(2-methylprop-2-en-1-yl)oxy]-6-phenylpyridine (CAS 344278-79-1)
- 4-Chlorotoluene-2,3,5,6-d4 (CAS 85577-24-8)
- 2-Pyridyl-2,8-bis(trifluoromethyl)-4-quinolyl ketone; [2,8-bis(Trifluoromethyl)-4-quinolyl]-2-pyridyl ketone; 2-Pyridinyl[2,8-bis(trifluoromethyl)-4-quinolinyl]methanone 35853-55-5 AB1006526 (CAS 35853-55-5)
- Semaglutide impurity 29 (CAS 1188328-22-4)
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