N-(4-Fluorophenyl)piperidine-1-sulfonamide CAS 446052-57-9
| CAS No. | 446052-57-9 |
| Molecular Formula | C11H15FN2O2S |
| Molecular Weight | 258.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(4-Fluorophenyl)piperidine-1-sulfonamide (CAS 446052-57-9), molecular formula C11H15FN2O2S and molecular weight 258.31 g/mol, is a CATO reference standard with documented purity and traceability.
N-(4-Fluorophenyl)piperidine-1-sulfonamide (C11H15FN2O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N-(4-Fluorophenyl)piperidine-1-sulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H15FN2O2S |
| Molecular Weight | 258.31 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related N Standards
- 1-((4-Fluorophenyl)sulfonyl)-4-methylpiperazine (CAS 125926-53-6)
- 2-{2-[(3-fluorophenyl)amino]ethyl}-1,2-thiazolidine-1,1-dione (CAS 1284857-69-7)
- (1-((3-Fluorophenyl)sulfonyl)pyrrolidin-3-yl)methanamine (CAS 1832067-64-7)
- 3-(4-Fluorophenyl)-6-methoxybenzo[b]thiophene (CAS 225222-82-2)
- n-[(4-fluorophenyl)methyl]-1,3-benzothiazol-2-amine (CAS 923893-82-7)
- (4-Fluorophenyl)-(4-isopropoxyphenyl)-methanone (CAS 1097018-70-6)
- 1143577-53-0 4-(3-Fluorophenyl)-6-piperazin-1-ylpyrimidine MFCD14281641 (CAS 1143577-53-0)
- 4-(4-Fluorophenyl)-6-(piperazin-1-yl)pyrimidine (CAS 1143577-57-4)
Recommended Standards
- n-(3-Fluoro-4-methylphenyl)-1,3-benzothiazol-2-amine (CAS 852399-68-9)
- N-[(1S)-1-(Hydroxymethyl)-2-[(3S)-2-oxo-3-pyrrolidinyl]ethyl]-carbamic Acid tert-Butyl Ester (CAS 249736-45-6)
- Methyl 5-((tert-butoxycarbonyl)amino)piperidine-3-carboxylate (CAS 903094-67-7)
- Methyl 3,4,5-Trimethoxycinnamate (CAS 20329-96-8)
- 4,4'-Bis(oxiran-2-ylmethoxy)-1,1'-biphenyl (CAS 2461-46-3)
- 1-(2-(Chloromethyl)phenyl)-1H-imidazole hydrochloride (CAS 1956322-83-0)
- 6-(Trifluoromethyl)-1h,2h,3h,9h-pyrrolo[2,1-b]quinazolin-9-one (CAS 730992-47-9)
- methyl trans-4-methylsulfonyloxycyclohexanecarboxylate (CAS 2787521-93-9)
- Dichloro[1,2-bis(diethylphosphino)ethane]nickel(II) (CAS 37504-45-3)
- (4-Methyl-1,2,3-thiadiazol-5-yl)(1,5-dioxa-9-azaspiro[5.5]undecan-9-yl)methanone (CAS 1351658-46-2)
- Latamoxef impurity 43 (CAS CATO-C4X-179843)
- 2-Hydrazinyl-3a,4,5,6,7,7a-hexahydro-1h-1,3-benzodiazole hydrobromide (CAS 99347-22-5)
- Trimethoprim lactate salt (CAS 23256-42-0)
- Osteogenic Growth Peptide (10-14) (CAS 105250-85-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com